Results 231 to 240 of about 740,269 (354)

KLK1 as an Epithelial‐Specific Brake Inhibits Colorectal Tumorigenesis by Suppressing B1R‐Mediated Fibroblast Phenotypic Transition

Advanced Science, EarlyView.
KLK1 downregulation disrupts the intestinal mucosal barrier and impairs kallikrein‐kinin signaling, thereby reducing Lys‐des‐Arg9‐BK production. This enhances B1R activation on ADAMDEC1⁺ fibroblasts, promoting inflammation and extracellular matrix (ECM) remodeling. The resulting iCAFs promote colorectal cancer progression, highlighting a novel KLK1‐B1R
Lisha Zhou, Meijing Wang, Shunji Liu, Limei Gu, Shijia Liu, Qianming Du, Tianyi Zhang, Yinuo Ma, Lixin Zhao, Jiaming Wang, Qiang Xu, Tingsheng Ling, Haibo Cheng, Hongqi Chen, Yang Sun   +14 more
wiley   +1 more source

A GAN-Based Approach for enhancing security in satellite based IoT networks using MPI enabled HPC. [PDF]

PLoS One
Ahmad SZ, Qamar F, Alshehri H, Jeribi F, Tahir A, Siddiqui ST, Ramakrishnan J.   +6 more
europepmc   +1 more source

Deciphering Neural Mechanisms Underlying Marmoset Dynamic Natural Behaviors Using a Miniaturized Wireless Large‐Scale Coverage Neural Recorder

Advanced Science, EarlyView.
This study introduces a miniaturized wireless neural recording system integrated with custom‐designed 120‐channel µECoG arrays, engineered for monitoring brain activities in freely behaving marmosets. The system can capture and characterize behavior‐specific neural signals, including drinking‐related activation, pre‐vocalization anticipatory responses,
Hongru Liu, Xinyuan Cao, Jiyong Li, Lingyi Zheng, Jingwei Li, Qianbing Li, Min Xie, Huimin Li, Xiaolong Wang, Yuyu Wu, Xiangyu Zhang, Yizheng Wang, Xize Gao, Tiancheng Sheng, Nianzhen Du, Chengao Xu, Kai Zhou, Jing Xu, Changxiang Yan, Lianqing Liu, Lixia Gao, Xinjian Li, Mingjun Zhang   +22 more
wiley   +1 more source

Neuromorphic Hebbian learning with magnetic tunnel junction synapses. [PDF]

Commun Eng
Zhou P, Edwards AJ, Mancoff FB, Aggarwal S, Heinrich-Barna SK, Friedman JS.   +5 more
europepmc   +1 more source

A Van Der Waals Broadband Infrared Optical Synapse Enabling Orientation Detection

Advanced Science, EarlyView.
An infrared optoelectronic synapse based on a graphene/CrOCl/graphene van der Waals heterostructure is reported to possess a broadband synaptic response range from the visible to the infrared (520–2000 nm), which can be used to achieve orientation and motion detections of a target mimicing the pit organ of a pit vapor.
Dan Guo, Wenjing Li, Pingfan Gu, Weikang Dong, Xuyan Rui, Kenji Watanabe, Takashi Taniguchi, Yu Ye, Fawei Zheng, Jiadong Zhou, Shoujun Zheng   +10 more
wiley   +1 more source

Tunnel enabled programmable switches obfuscate network topology to defend against link flooding reconnaissance in software defined networking. [PDF]

Sci Rep
Li X, Lee J, Son J, Lee Y.
europepmc   +1 more source

Engineering Bacteria as Living Therapeutics in Cancer Therapy

Advanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen, Jiaqi Chen, Yixuan Chen, Wenxuan Yuan, Jiao Zhang, Guoqing Wang, Zhuojun Dai   +6 more
wiley   +1 more source

Machine learning for improved path loss prediction in urban vehicle-to-infrastructure communication systems. [PDF]

Front Artif Intell
Ben Ameur M, Chebil J, Habaebi MH, Tahar JBH.   +3 more
europepmc   +1 more source

How Do the Evolution and Innovation of Social Network Analysis Matter to Computer Science and Communications?

, 2013
Romana Xerez
openalex   +2 more sources

Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells‐Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation

Advanced Science, EarlyView.
This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li, Maoxiang Xu, Boyu Cai, Xiangyu Li, Zhanping Liang, Xiaohuan Xia, Haitao Zhang, Zhiwen Zhang, Fei Tan, Jialin Charlie Zheng   +9 more
wiley   +1 more source