Results 111 to 120 of about 575,292 (267)
Development and assessment of CootVR, a virtual reality computer program for model building. [PDF]
Todd H, Emsley P.
europepmc +1 more source
Mathematician and inventor Charles Babbage's code sketches are the first attempt to specify how to mechanize complex algorithms with a computer.
openaire +2 more sources
Partial computation of programs [PDF]
This paper attempts to clarify the difference between partial and ordinary computation. Partial computation of a computer program is by definition "specializing a general program based upon its operating environment into a more efficient program". It also shows the usefulness of partial computation.
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
RDP5: a computer program for analyzing recombination in, and removing signals of recombination from, nucleotide sequence datasets. [PDF]
Martin DP +8 more
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The paper deals with up-to-date questions concerning the effective introduction of the newest information technologies, system complexes and computer programs into management of general education establishment.
Zoya V. Savchenko
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

