Results 131 to 140 of about 8,437,425 (300)

USE OF INFORMATION – COMMUNICATIVE TECHNOLOGIES IN ADMINISTRATIVE ACTIVITY OF THE GENERAL EDUCATION ESTABLISHMENT

open access: yesІнформаційні технології і засоби навчання, 2010
The paper deals with up-to-date questions concerning the effective introduction of the newest information technologies, system complexes and computer programs into management of general education establishment.
Zoya V. Savchenko
doaj  

Artificial intelligence in oncology: global experience and future prospects

open access: yesФармакоэкономика
Objective: To analyze foreign experience in the use of artificial intelligence (AI) in oncology, as well as examine current advances in AI and its impact on clinical practice.Material and methods. A systematic review of foreign literature was carried out,
D. I. Korabelnikov, A. I. Lamotkin
doaj   +1 more source

RDP5: a computer program for analyzing recombination in, and removing signals of recombination from, nucleotide sequence datasets. [PDF]

open access: yesVirus Evol, 2021
Martin DP   +8 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Computer Engineering Bachelor\u27s Degree Academic Program Review, 2019

open access: yes, 2020
This report reviews Wright State University\u27s Computer Engineering Bachelor\u27s Degree program, specifically looking at the time from Fall 2015 to Fall ...
College of Engineering and Computer Science, Wright State University
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Computer Science and Engineering Doctoral Degree Academic Program Review, 2019

open access: yes, 2020
This report reviews Wright State University\u27s Computer Science and Engineering Doctoral program, specifically looking at the time from Fall 2015 to Fall ...
College of Engineering and Computer Science, Wright State University
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

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