Results 121 to 130 of about 3,311,825 (293)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

JPKWIC - General key word in context and subject index report generator [PDF]

open access: yes, 1968
JPKWIC computer program is a general key word in context and subject index report generator specifically developed to help nonprogrammers and nontechnical personnel to use the computer to access files, libraries and mass documentation.
Jirka, R.   +3 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Documentation of computer program GRIDDEL [PDF]

open access: yes
The GRIDDEL computer program which generates finite element meshes for NASTRAN in a manner convenient to the study of laminated composite flat plates is discussed. The program is capable of creating 8 node HEXA elements, GRID coordinates, and PSOLID data
Baumann, K. J.
core   +1 more source

Computer program for high pressure real gas effects [PDF]

open access: yes, 1969
Computer program obtains the real-gas isentropic flow functions and thermodynamic properties of gases for which the equation of state is known. The program uses FORTRAN 4 subroutines which were designed for calculations of nitrogen and helium.
Johnson, R. C.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

RDP5: a computer program for analyzing recombination in, and removing signals of recombination from, nucleotide sequence datasets. [PDF]

open access: yesVirus Evol, 2021
Martin DP   +8 more
europepmc   +1 more source

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