Results 111 to 120 of about 35,870,954 (296)

Principles for design of software engineering visualization tools

, 2000
Thesis (M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2000.Includes bibliographical references (leaves 60-71).by Jeffrey Howard.M ...
Howard, Jeffrey (Jeffrey Rush), 1977-
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Guidelines for using empirical studies in software engineering education [PDF]

, 2017
Software engineering education is under constant pressure to provide students with industry-relevant knowledge and skills. Educators must address issues beyond exercises and theories that can be directly rehearsed in small settings. Industry training has
Jürgen Münch, Fagerholm, Fabian, Fabian Fagerholm, Marco Kuhrmann, Kuhrmann, Marco, Münch, Jürgen   +5 more
core   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Analyzing the 2021 Kaseya Ransomware Attack: Combined Spearphishing Through SonicWall SSLVPN Vulnerability

IET Information Security
In July 2021, the IT management software company Kaseya was the victim of a ransomware cyberattack. The perpetrator of this attack was ransomware evil (REvil), an allegedly Russian-based ransomware threat group. This paper addresses the general events of
Suman Bhunia, Matthew Blackert, Henry Deal, Andrew DePero, Amar Patra   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

MATADOR: a magic matrix-based framework for tamper detection and image recovery

Journal of King Saud University: Computer and Information Sciences
Ensuring the integrity and authenticity of digital medical images is crucial for healthcare security and digital forensics, as image tampering can have serious consequences.
Thilina Mendis, Farah Kandah, Lalith Medury   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Automatic Sugarcane Disease Detection and Outbreak Alert System using Deep Learning

JISR on Computing
Agriculture Agriculture is a vital sector in Pakistan, with sugarcane being the second-largest crop. However, the industry faces challenges due to crop diseases, prompting the need for innovative solutions.
Munaf Rashid, Zuha Khan, Saeed Usmani, Asadullah Maliyawala, Kashif Iqbal   +4 more
doaj   +1 more source

N-ary level in the software test vehicle for the Infoplex database computer [PDF]

, 1982
Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1982.MICROFICHE COPY AVAILABLE IN ARCHIVES AND ENGINEERINGIncludes bibliographical references.by David Lui.B ...
Lui, David
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