Results 91 to 100 of about 10,600,895 (351)
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, EarlyView.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
Mathematical Logic in Computer Science [PDF]
arXiv, 2018 The article retraces major events and milestones in the mutual influences between mathematical logic and computer science since the 1950s.
arxiv
FEBS Letters, EarlyView.The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang +9 more
wiley +1 more source
A Simple Algorithm for Consistent Query Answering under Primary Keys [PDF]
Logical Methods in Computer ScienceWe consider the dichotomy conjecture for consistent query answering under primary key constraints. It states that, for every fixed Boolean conjunctive query q, testing whether q is certain (i.e.
Diego Figueira +3 more
doaj +1 more source
The Complexity of All-switches Strategy Improvement [PDF]
Logical Methods in Computer Science, 2018 Strategy improvement is a widely-used and well-studied class of algorithms for solving graph-based infinite games. These algorithms are parameterized by a switching rule, and one of the most natural rules is "all switches" which switches as many edges as
John Fearnley, Rahul Savani
doaj +1 more source
arXiv, 2015 Data science is gaining more and more and widespread attention, but no consensus viewpoint on what data science is has emerged. As a new science, its objects of study and scientific issues should not be covered by established sciences. Data in cyberspace have formed what we call datanature.
arxiv
Ubiquity symposium: The science in computer science: unplugging computer science to find the science [PDF]
Ubiquity, 2014 The Computer Science Unplugged project provides activities that enable students to engage with concepts from computer science without having to program. Many of the activities provide the basis of a scientific exploration of computer science, and thus help students to see the relationship of the discipline with science.
openaire +3 more sources
Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
FEBS Letters, EarlyView.Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka +6 more
wiley +1 more source
ABET Accreditation: A Way Forward for PDC Education [PDF]
EduPar-21: 11th NSF/TCPP Workshop on Parallel and Distributed
Computing Education, May 2021, 2021 With parallel and distributed computing (PDC) now wide-spread, modern computing programs must incorporate PDC within the curriculum. ACM and IEEE Computer Society's Computer Science curricular guidelines have recommended exposure to PDC concepts since 2013.
arxiv
, 2018 The Rube Goldberg Machine: The 90 year old concept’s lessons for the engineering student --Solar Power!?
School of Computer Science & Engineering,
core +1 more source