Results 111 to 120 of about 10,839,512 (369)

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Informaticology: combining Computer Science, Data Science, and Fiction Science

open access: yes, 2012
Motivated by an intention to remedy current complications with Dutch terminology concerning informatics, the term informaticology is positioned to denote an academic counterpart of informatics where informatics is conceived of as a container for a ...
Bergstra, Jan A.
core  

Adaptive jukebox : a context-sensitive playlist generator [PDF]

open access: yes, 2007
Nowadays, a lot of users own large collections of music MP3 files. Manually organising such collections into playlists is a tedious task. On the other hand random playlist generation may not always provide the user with an enjoyable experience. Automatic
5th Computer Science Annual Workshop (CSAW’07)   +1 more
core  

Computational Archival Science [PDF]

open access: yesModerna arhivistika, 2018
The digitisation of archival materials and ingest of digitally born materials in digital archives has led to the possibilities of application of the big data analytical principles in the digital archives. The author explains the 5V characteristics of big data. He proceeds to define the concept of Computational Archival Science (CAS).
openaire   +2 more sources

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Is computer science dying? [PDF]

open access: yes2016 International Conference on Embedded Computer Systems: Architectures, Modeling and Simulation (SAMOS), 2016
This talk discusses some positive and negative trends in the field. It briefly examines some case studies, and finally discusses things that we as a community could do better.
openaire   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Implementing “The MATRIX” [PDF]

open access: yes, 2003
In this technical note we shall be considering how the asynchronous constructs of the Hoopla language can be combined with concurrency constructs of parallel languages to implement a framework which allows programmers to write programs which interact ...
1st Computer Science Annual Workshop (CSAW’03)   +1 more
core  

Maps of Computer Science

open access: yes2014 IEEE Pacific Visualization Symposium, 2014
10 pages, 8 figures, live version and source code available at mocs.cs.arizona ...
Stephen G. Kobourov, Daniel Fried
openaire   +3 more sources

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