Results 111 to 120 of about 10,839,512 (369)
Brucella NyxA and NyxB dimerization enhances effector function during infection
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre+4 more
wiley +1 more source
Informaticology: combining Computer Science, Data Science, and Fiction Science
Motivated by an intention to remedy current complications with Dutch terminology concerning informatics, the term informaticology is positioned to denote an academic counterpart of informatics where informatics is conceived of as a container for a ...
Bergstra, Jan A.
core
Adaptive jukebox : a context-sensitive playlist generator [PDF]
Nowadays, a lot of users own large collections of music MP3 files. Manually organising such collections into playlists is a tedious task. On the other hand random playlist generation may not always provide the user with an enjoyable experience. Automatic
5th Computer Science Annual Workshop (CSAW’07)+1 more
core
Computational Archival Science [PDF]
The digitisation of archival materials and ingest of digitally born materials in digital archives has led to the possibilities of application of the big data analytical principles in the digital archives. The author explains the 5V characteristics of big data. He proceeds to define the concept of Computational Archival Science (CAS).
openaire +2 more sources
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg+2 more
wiley +1 more source
Is computer science dying? [PDF]
This talk discusses some positive and negative trends in the field. It briefly examines some case studies, and finally discusses things that we as a community could do better.
openaire +3 more sources
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Implementing “The MATRIX” [PDF]
In this technical note we shall be considering how the asynchronous constructs of the Hoopla language can be combined with concurrency constructs of parallel languages to implement a framework which allows programmers to write programs which interact ...
1st Computer Science Annual Workshop (CSAW’03)+1 more
core
10 pages, 8 figures, live version and source code available at mocs.cs.arizona ...
Stephen G. Kobourov, Daniel Fried
openaire +3 more sources