Results 111 to 120 of about 10,600,895 (351)
Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions
FEBS Letters, EarlyView.This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten +10 more
wiley +1 more source
FAIR and Open Computer Science Research Software [PDF]
arXiv, 2019 In computational science and in computer science, research software is a central asset for research. Computational science is the application of computer science and software engineering principles to solving scientific problems, whereas computer science is the study of computer hardware and software design. The Open Science agenda holds that science
arxiv
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin +2 more
wiley +1 more source
COMPUTER SCIENCE IN THE EDUCATION OF UKRAINE: FORMATION PROSPECTS
Ìнформаційні технології в освіті, 2016 The article deals with the formation of computer science as science and school subject as well in the system of education in Ukraine taking into consideration the development tendencies of this science in the world.
Viktor Shakotko
doaj
Visualization in Computational Science
Procedia Computer Science, 2010 AbstractThis section and the papers that follow relate to to the workshop on Visualization in Computational Science which is held at the Tenth International Conference on Computational Science (ICCS2010) in Amsterdam, the Netherlands. This workshop brings together experts from visualization research and end-users to illustrate the state of the art and ...
openaire +2 more sources
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
The Application of Computers to Medical and Veterinary Science [Abridged] [PDF]
, 1963 F.A. Nash
openalex +2 more sources
, 2019 https://scholarlycommons.pacific.edu/the-rock/1005/thumbnail ...
School of Engineering and Computer Science
core +1 more source
Computer science in Dutch secondary education: independent or integrated? [PDF]
, 1992 Nowadays, in Dutch secondary education, computer science is integrated within school subjects. About ten years ago computer science was considered an independent subject, but in the mid-1980s this idea changed.
Doornekamp, B. Gerard +1 more
core +2 more sources