The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Bridging Domains: Advances in Explainable, Automated, and Privacy-Preserving AI for Computer Science and Cybersecurity [PDF]
Youssef Harrath +3 more
openalex +1 more source
Computer resources for supporting student conversations about science concepts [PDF]
Shelley Goldman
openalex +1 more source
Ancestral Computing for Sustainability: Centering Indigenous Epistemologies in Researching Computer Science Education. [PDF]
López-Quiñones A +9 more
europepmc +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
An Effective Model for Computer System Building Projects in Computer Engineering and Computer Science [PDF]
Yul Chu, Jin Hwan Park
openalex +1 more source
Cognitive context and impulsivity in adolescence: a comparative study of drama and computer science students using the Barratt Impulsiveness Scale. [PDF]
Munteanu AM +5 more
europepmc +1 more source
FluoRender Script: A Case Study of Lingua Franca in Translational Computer Science. [PDF]
Wan Y, Holman HA, Hansen C.
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

