Results 81 to 90 of about 10,839,512 (369)

COMPUTATIONAL SCIENCE CENTER [PDF]

open access: yes, 2004
The Brookhaven Computational Science Center brings together researchers in biology, chemistry, physics, and medicine with applied mathematicians and computer scientists to exploit the remarkable opportunities for scientific discovery which have been enabled by modern computers.
openaire   +7 more sources

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Enabling usage of cloud-based applications when offline [PDF]

open access: yes, 2014
The Internet is ubiquitous. Office and home environments are increasingly making use of cloud computing platforms to facilitate day to day tasks. The main cloud related challenges highlighted by academia include: server consolidation, energy management ...
Computer Science Annual Workshop CSAW’14   +1 more
core  

Computer Science vs. COVID-19 [PDF]

open access: yesBulletin of the Polish Academy of Sciences: Technical Sciences, 2021
Aneta Afelt   +5 more
doaj   +1 more source

The First-Order Theory of Ground Tree Rewrite Graphs [PDF]

open access: yesLogical Methods in Computer Science, 2014
We prove that the complexity of the uniform first-order theory of ground tree rewrite graphs is in ATIME(2^{2^{poly(n)}},O(n)). Providing a matching lower bound, we show that there is some fixed ground tree rewrite graph whose first-order theory is hard ...
Stefan Göller, Markus Lohrey
doaj   +1 more source

Expanding capacity and promoting inclusion in introductory computer science: a focus on near-peer mentor preparation and code review

open access: yesComputer Science Education, 2017
A dilemma within computer science departments is developing sustainable ways to expand capacity within introductory computer science courses while remaining committed to inclusive practices. Training near-peer mentors for peer code review is one solution.
Heather Pon-Barry   +2 more
semanticscholar   +1 more source

Computational Thinking in Science

open access: yesAmerican Scientist, 2017
A quiet but profound revolution has been taking place throughout science. The computing revolution has transformed science by enabling all sorts of new discoveries through information technology. Throughout most of the history of science and technology, there have been two types of characters.
openaire   +3 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Universal First-Order Logic is Superfluous for NL, P, NP and coNP [PDF]

open access: yesLogical Methods in Computer Science, 2014
In this work we continue the syntactic study of completeness that began with the works of Immerman and Medina. In particular, we take a conjecture raised by Medina in his dissertation that says if a conjunction of a second-order and a first-order ...
Nerio Borges, Blai Bonet
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

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