Results 41 to 50 of about 35,580 (260)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Analysis of Grover’s Algorithm and Quantum Computation [PDF]

open access: yes, 2019
Quantum computation compared to many other fields in computer science, have been under researched caused by the physical limitations of technology, and the complexity/difficulty of the topic itself. As quantum computers/computing starts to advance in the
Kevin, Ali
core  

On the construction of decentralised service-oriented orchestration systems [PDF]

open access: yes, 2016
Modern science relies on workflow technology to capture, process, and analyse data obtained from scientific instruments. Scientific workflows are precise descriptions of experiments in which multiple computational tasks are coordinated based on the ...
Jaradat, Ward
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

A Parallel semantics for normal logic programs plus time [PDF]

open access: yes, 2013
It is proposed that Normal Logic Programs with an explicit time ordering are a suitable basis for a general purpose parallel programming language. Examples show that such a language can accept real-time external inputs and outputs, and mimic assignment ...
Cleary, John G.   +2 more
core  

Models of computation: A numeric analysis and performance evaluation [PDF]

open access: yes
This research seeks to better understand what drives performance in computation. To develop this understanding the researcher investigates the literature on computational performance within the classical and quantum paradigm for both binary and multi ...
Verschueren, Ricardo
core   +2 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Computability, complexity, and languages: fundamentals of theoretical computer science

open access: yes, 1983
Computability, Complexity, and Languages: Fundamentals of Theoretical Computer Science provides an introduction to the various aspects of theoretical computer science. Theoretical computer science is the mathematical study of models of computation.
Rheinboldt, Werner   +2 more
core  

Building a Scalable Game Engine to Teach Computer Science Languages

open access: yesIEEE Revista Iberoamericana de Tecnologias del Aprendizaje, 2015
Every day, more people are interested in learning computer science (CS), either to improve their skill set to apply for new jobs or just for personal growth. The sector of the population looking for instruction on these subjects has increased and diversified.
Torrente, Javier   +3 more
openaire   +3 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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