Results 51 to 60 of about 31,041 (265)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
An algebraic basis for specifying and enforcing access control in security systems
Security services in a multi-user environment are often based on access control mechanisms. Static aspects of an access control policy can be formalised using abstract algebraic models.
Pahl, Claus
core
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Towards sharing in lazy computation systems
Work on proving congruence of bisimulation in functional programming languages often refers to [How89,How96], where Howe gave a highly general account on this topic in terms of so-called lazy computation systems .
Mann, Matthias, Matthias Mann
core
Language Cognition and Language Computation Human and Machine Language Understanding
anguage="eng" data-ev-field="abstract">Language understanding is a key scientific issue in the fields of cognitive and computer science.
Nai Ding +4 more
core
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Prefix probabilities for linear context-free rewriting systems
We present a novel method for the computation of prefix probabilities for linear context-free rewriting systems. Our approach streamlines previous procedures to compute prefix probabilities for context-free grammars, synchronous context-free grammars and
Satta, Giorgio +2 more
core
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Techniques for design and validation of quantum protocols [PDF]
Our objective in this thesis is to perform formal specification and automated validation of the class of protocols associated with quantum cryptography.
Papanikolaou, Nikolaos K.
core

