Results 41 to 50 of about 3,229,818 (297)
Reference standards and reference multipliers for the comparison of the citation impact of papers published in different time periods [PDF]
Journal of the American Society for Information Science and Technology, 2010 AbstractIn this study, reference standards and reference multipliers are suggested as a means to compare the citation impact of earlier research publications in physics (from the period of “Little Science” in the early 20th century) with that of contemporary papers (from the period of “Big Science,” beginning around 1960).
Jin-Xing Hao +3 more
openaire +29 more sources
Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
FEBS Letters, Volume 599, Issue 8, Page 1146-1158, April 2025.Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka +6 more
wiley +1 more source
On the strength of proof-irrelevant type theories [PDF]
Logical Methods in Computer Science, Volume 4, Issue 3 (September
26, 2008) lmcs:1142, 2008 We present a type theory with some proof-irrelevance built into the conversion rule. We argue that this feature is useful when type theory is used as the logical formalism underlying a theorem prover. We also show a close relation with the subset types of the theory of PVS.
arxiv +1 more source
FEBS Letters, Volume 599, Issue 8, Page 1113-1121, April 2025.The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley +2 more
wiley +1 more source
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, Volume 599, Issue 9, Page 1269-1284, May 2025.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
Science in Computational Sciences [PDF]
, 2012 The existing theory in relation to science presents the physics as an ideal, although many sciences not approach the same, so that the current philosophy of science-Theory of Science- is not much help when it comes to analyze the computer science, an ...
Jameson Cerrosen, Jia Pong
core
FEBS Letters, Volume 599, Issue 7, Page 1006-1028, April 2025.This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause +2 more
wiley +1 more source
Algebraic Geometry and Representation theory in the study of matrix multiplication complexity and other problems in theoretical computer science [PDF]
arXiv, 2021 Many fundamental questions in theoretical computer science are naturally expressed as special cases of the following problem: Let $G$ be a complex reductive group, let $V$ be a $G$-module, and let $v,w$ be elements of $V$. Determine if $w$ is in the $G$-orbit closure of $v$.
arxiv
Philosophy, Computing and Information Science
, 2015 The historical development has lead to the decay of Natural Philosophy which until 19th century included all of our knowledge about the physical world into the growing multitude of specialized sciences. The focus on the in-depth enquiry disentangled from its broad context lead to the problem of loss of common world-view and impossibility of ...
Micah Clark +2 more
openaire +7 more sources
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source