Results 121 to 130 of about 498,375 (267)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

AutoMatch: Automated Matching of Compute Kernels to Heterogeneous HPC Architectures

, 2016
HPC systems contain a wide variety of heterogeneous computing resources, ranging from general-purpose CPUs to specialized accelerators. Porting sequential applications to such systems for achieving high performance requires significant software and ...
Feng, Wu-chun, Hanafy, Yasser Y., Jung, Changhee, Helal, Ahmed E.   +3 more
core  

A deep learning-based automated Solar-Powered Fish Monitoring System. [PDF]

PLoS One
Ahene E, Agyei RO, Gyening ROM, Obirikorang KA, Takyi K, Owusu-Agyemang K, Amoako-Banning L, Walker J.   +7 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Increasing the Precision of Distant Pointing for Large High-Resolution Displays

, 2008
Distant pointing at large displays allows rapid cursor movements, but can be problematic when high levels of precision are needed, due to natural hand tremor and track-ing jitter.
Bowman, Douglas A., Kopper, Regis, Silva, Mara G., McMahan, Ryan Patrick   +3 more
core  

QSyncFold: quantum neural network for multidimensional sync-discovery in protein folding. [PDF]

Brief Bioinform
Shi J, Du P, Zeng W, Wang W, Peng S, Li X.   +5 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Computer Network Performance Evaluation based on Datarate and Number of Clients Per Server using OMNeT++ Simulation Environment

, 2014
We present the performance of Computer network using OMNeT++ network simulation framework and Nclient application module from INET framework for our experiment.
Mr. Dhobale J. V., Dr. Kalyankar N. V.
core  

A novel adaptive quasi-Newton-type update and its global convergence without Lipschitz condition for constrained system of nonlinear monotone equations. [PDF]

PLoS One
Ahmed K, Semary HE, Al-Moisheer AS, Ibrahim SM, Halilu AS, Waziri MY, Mohamed MA, Murtala S.   +7 more
europepmc   +1 more source

Vecpar'08: High Performance Computing for Computational Science

Bollettino del CILEA, 2008
Dal 24 al 27 Giugno 2008 si è tenuto a Tolosa, presso l’ENSEEIHT Ecole Nationale Supérieure d’Electrotechnique, d’Electronique, d’Informatique, d’Hydraulique et des Téléccomunications di Tolosa, l’ ottava conferenza internazionale di calcolo ad alte prestazioni per la scienza computazionale.
openaire   +1 more source