Results 51 to 60 of about 87,820 (213)
Intellectual structure and subject themes in information systems research : a journal cocitation study [PDF]
, 2005 Information Systems (IS) is a discipline in which research and practice are closely intertwined. IS is also closely related to and overlapping several other disciplines, including Information Science. Thus, IS provides an excellent case for examining the
Wilson, Concepción S. +2 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Activity based interfaces in online social networks [PDF]
, 2007 Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2007.Includes bibliographical references (p. 51).The goal of the project is to explore how activity-based interfaces can create more meaningful
Laraqui, Jawad
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Social networks and statistical relational learning: a survey
, 2012 One of the most appreciated functionality of computers nowadays is their being a means for communication and information sharing among people. With the spread of the Internet, several complex interactions have taken place among people, giving rise to ...
ESPOSITO, Floriana +3 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Clustering social networks using interaction semantics and sentics
, 2012 The passage from a static read-only Web to a dynamic read-write Web gave birth to a huge amount of online social networks with the ultimate goal of making communication easier between people with common interests.
Hussain, Amir +8 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
On the integration of the Internet into informal science communication [PDF]
The present analysis looks at how scientists use the Internet for informal scientific communication. It investigates the relationship between several explanatory variables and Internet use for social communication, information retrieval and information ...
Barjak, Franz
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