Results 61 to 70 of about 78,623 (223)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Trailblazing through a Knowledge Space of Science: Forward Citation Expansion in CiteSeer [PDF]
Understanding emerging trends and patterns in science and technology is essential not only to scientists and engineers in their own fast-advancing fields but also to a wide variety of individuals and organizations who are also interested in tracking the ...
Chen, Chaomei, Lin, Xia, Zhu, Weizhong
core
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Social scientists at work on the electronic network [PDF]
The purpose of this article is to contribute to our stock of knowledge about who uses networks, how they are used, and what contribution the networks make to advancing the scientific enterprise.
Robbin, Alice
core
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Supporting Meaningful Social Networks
Recent years have seen exponential growth of social network sites (SNSs) such as Friendster, MySpace and Facebook. SNSs flatten the real-world social network by making personal information and social structure visible to users outside the ego-centric ...
Huang, Yongjian
core
The collaboration among individuals is essential to maximize economic efficiency. Today most of the technological and economical advancements require multidisciplinary efforts.
Ayvaz, Demet +2 more
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
A New Centrality Measure for Social Network Analysis Applicable to Bibliometric and Webometric Data
In the literature there are a large number of publications in sociology, in computer science or in information sciences, as well as in studies of collaboration in science describing the studies of social networks with unweighted ties because measures ...
Theo Kretschmer +3 more
core
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source

