Results 71 to 80 of about 87,820 (213)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Supporting Meaningful Social Networks
Recent years have seen exponential growth of social network sites (SNSs) such as Friendster, MySpace and Facebook. SNSs flatten the real-world social network by making personal information and social structure visible to users outside the ego-centric ...
Huang, Yongjian
core +1 more source
, 2009 Unlike the telephone network or the Internet, many of the next generation networks are not engineered for the purpose of providing efficient communication between various networked entities. Examples abound: sensor networks, peer-to-peer networks, mobile
Shah, Devavrat, Devavrat Shah
core +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
How Can Social Networks Ever Become Complex? Modelling the Emergence of Complex Networks from Local Social Exchanges [PDF]
Small-world and power-law network structures have been prominently proposed as models of large networks. However, the assumptions of these models usually lack sociological grounding.
Ramon Sang�esa +3 more
core
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Social delay-tolerant network routing [PDF]
, 2011 Paper presented at the 2nd ICC Winter Workshop on Complexity in Social SystemsRouting in mobile delay-tolerant networks faces new challenges such as mobility and the dynamic nature of the network.
Bigwood, Gregory John +2 more
core +2 more sources
Encryption for Peer-to-Peer Social Networks
, 2012 To address privacy concerns over online social networking services, several decentralized alternatives have been proposed. These peer-to-peer (P2P) online social networks do not rely on centralized storage of user data.
Oleksandr Bodriagov +3 more
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source