Results 71 to 80 of about 78,623 (223)

On the integration of the Internet into informal science communication

The present analysis looks at how scientists use the Internet for informal scientific communication. It investigates the relationship between several explanatory variables and Internet use for social communication, information retrieval and information ...
Barjak, Franz
core  

Construction of a support tool for the design of the activity structures based computer system architectures [PDF]

, 1986
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.This thesis is a reapproachment of diverse design concepts, brought to bear upon the computer system engineering problem of identification and control ...
Mohamad, Sabah Mohamad Amin
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Social networks in transnational and virtual communities

, 2003
There has been extensive research on social networks but little is known about why some communities survive and some disintegrate. This paper provides a framework to explain similarities in many types of communities.
Sudweeks, F., Fay Sudweeks, Nathan Vivian, Vivian, N.   +3 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Social delay-tolerant network routing

, 2011
Paper presented at the 2nd ICC Winter Workshop on Complexity in Social SystemsRouting in mobile delay-tolerant networks faces new challenges such as mobility and the dynamic nature of the network.
Bigwood, Gregory John, Henderson, Tristan Nicholas Hoang, Bhatti, Saleem Noel   +2 more
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

From diversity to convergence : British computer networks and the Internet, 1970-1995 [PDF]

The Internet's success in the 21st century has encouraged analysts to investigate the origin of this network. Much of this literature adopts a teleological approach.
Rutter, Dorian James
core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source