Results 31 to 40 of about 1,361,155 (249)

Teaching MDE through the Formal Verification of Process Models [PDF]

open access: yes, 2011
International audienceModel Driven Engineering (MDE) and formal methods (FM) play a key role in the development of Safety Critical Systems (SCS). They promote user oriented abstraction and formal specification using Domain Specific Modeling Languages ...
Combemale, Benoit   +4 more
core   +4 more sources

Seeing beyond Computer Science and Software Engineering [PDF]

open access: yes, 2009
The boundaries of computer science are defined by what symbolic computation can accomplish. Software Engineering is concerned with effective use of computing technology to support automatic computation on a large scale so as to construct desirable solutions to worthwhile problems. Both focus on what happens within the machine.
openaire   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Microservices and Machine Learning Algorithms for Adaptive Green Buildings [PDF]

open access: yes, 2019
In recent years, the use of services for Open Systems development has consolidated and strengthened. Advances in the Service Science and Engineering (SSE) community, promoted by the reinforcement of Web Services and Semantic Web technologies and the ...
Alonso Montesinos, Joaquín Blas   +6 more
core   +1 more source

"Boring formal methods" or "Sherlock Holmes deduction methods"?

open access: yes, 2016
This paper provides an overview of common challenges in teaching of logic and formal methods to Computer Science and IT students. We discuss our experiences from the course IN3050: Applied Logic in Engineering, introduced as a "logic for everybody ...
BF Sherman   +11 more
core   +1 more source

Innovations in Computing Sciences and Software Engineering [PDF]

open access: yes, 2010
Innovations in Computing Sciences and Software Engineering includes a set of rigorously reviewed world-class manuscripts addressing and detailing state-of-the-art research projects in the areas of Computer Science, Software Engineering, Computer Engineering, and Systems Engineering and Sciences.
openaire   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

EPICS: A Service Learning Program at Butler University [PDF]

open access: yes, 2005
In this paper we present our experiences teaching EPICS (Engineering Projects In Community Service) at Butler University, a small, private university, from within the Department of Computer Science and Software Engineering.
Linos, Panos K, Sorenson, Jonathan P
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy