Results 51 to 60 of about 1,420,326 (306)

‘Follow the Moon’ Development: Writing a Systematic Literature Review on Global Software Engineering Education [PDF]

open access: yes, 2015
This presentation reflects on method and practice in Computer Science Education Research, through introducing the process of conducting a Systematic Literature Review.
Beecham S., Clear T., Noll J.
core   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Teaching MDE through the Formal Verification of Process Models [PDF]

open access: yes, 2011
International audienceModel Driven Engineering (MDE) and formal methods (FM) play a key role in the development of Safety Critical Systems (SCS). They promote user oriented abstraction and formal specification using Domain Specific Modeling Languages ...
Combemale, Benoit   +4 more
core   +4 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

"Continuous" Integration of Scientific Software (in Computational Science and Engineering)

open access: yes, 2022
A presentation describing the use of Continuous Integration for scientific (research) software in Computational Science and Engineering. It links to the Knowledge Base (https://knowledge-base.nfdi4ing.de/) wherein this workflow is presented.
Schwarzmeier, Moritz   +8 more
openaire   +1 more source

EPICS: A Service Learning Program at Butler University [PDF]

open access: yes, 2005
In this paper we present our experiences teaching EPICS (Engineering Projects In Community Service) at Butler University, a small, private university, from within the Department of Computer Science and Software Engineering.
Linos, Panos K, Sorenson, Jonathan P
core   +1 more source

"Boring formal methods" or "Sherlock Holmes deduction methods"?

open access: yes, 2016
This paper provides an overview of common challenges in teaching of logic and formal methods to Computer Science and IT students. We discuss our experiences from the course IN3050: Applied Logic in Engineering, introduced as a "logic for everybody ...
BF Sherman   +11 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

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