Results 81 to 90 of about 1,420,326 (306)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Proceedings of the 4th Workshop for Young Scientists in Computer Science & Software Engineering (CS&SE@SW 2021), Virtual Event, Kryvyi Rih, Ukraine, December 18, 2021 [PDF]

open access: bronze, 2022
Арнольд Юхимович Ків   +4 more
openalex   +1 more source

Research in computer science [PDF]

open access: yes
Synopses are given for NASA supported work in computer science at the University of Virginia. Some areas of research include: error seeding as a testing method; knowledge representation for engineering design; analysis of faults in a multi-version ...
Ortega, J. M.
core   +1 more source

Collaborative Verification-Driven Engineering of Hybrid Systems

open access: yes, 2014
Hybrid systems with both discrete and continuous dynamics are an important model for real-world cyber-physical systems. The key challenge is to ensure their correct functioning w.r.t. safety requirements.
Mitsch, Stefan   +2 more
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Third international workshop on software engineering for computational science and engineering

open access: yesProcedia Computer Science, 2010
AbstractThis workshop focuses on bringing together members of the software engineering community with members of the computational science and engineering community to discuss approaches for developing computational science & engineering software. The workshop provides a venue for members of these communities, who do not normally interact, to meet and ...
openaire   +2 more sources

4-H Computer & Internet Project [PDF]

open access: yes, 2018
Knowing how to operate a computer and write code is quickly becoming a required 21st century skill. A 4-H computer project will help you learn about software and/or hardware topics •Learn about computer hardware •Explore and learn to navigate an ...
Borba, John   +7 more
core  

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