Results 91 to 100 of about 4,042,014 (292)

Nice to know [PDF]

open access: yes, 2008
The byproduct of today’s massive interconnectivity is that basically nothing and no-one is immune to cyber attacks any longer. Sadly, this can be demonstrated rather trivially.
Etalle, Sandro
core   +2 more sources

Authorial voice in academic writing: A comparative study of journal articles in English Literature and Computer Science [PDF]

open access: yesIbérica, 2020
Academic writers represent themselves in their texts in different ways, notably through use of first person pronouns to construct an authorial voice and enhance arguments.
Yin Ling Cheung , Louwena Lau
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Computational Visualistics: Dealing with Pictures in Computer Science [PDF]

open access: yes, 2005
Building blocks from many disciplines have to be integrated into a general science of images. Computational visualistics has been formed as a contributing field embracing all aspects of dealing with images computationally.
Schirra, Dr Jörg R.J.
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Using Technology as a Vehicle to Appropriately Integrate Mathematics and Science Instruction for the Middle School [PDF]

open access: yes, 1999
At the College of William and Mary, pre-service middle school science and mathematics teachers enroll in their respective methods courses taught in the same time period.
Giese, R. N., Mason, M. M.
core   +1 more source

Advances in Artificial Intelligence Require Progress Across all of Computer Science

open access: yes, 2017
Advances in Artificial Intelligence require progress across all of computer science.
Hager, Gregory D.   +4 more
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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