Results 91 to 100 of about 5,026,987 (343)

Molecular signature comprising 11 platelet-genes enables accurate blood-based diagnosis of NSCLC

BMC Genomics, 2020
Background Early diagnosis is crucial for effective medical management of cancer patients. Tissue biopsy has been widely used for cancer diagnosis, but its invasive nature limits its application, especially when repeated biopsies are needed.
Chitrita Goswami, Smriti Chawla, Deepshi Thakral, Himanshu Pant, Pramod Verma, Prabhat Singh Malik, Jayadeva ▮, Ritu Gupta, Gaurav Ahuja, Debarka Sengupta   +9 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Recruitment, Preparation, Retention: A case study of computing culture at the University of Illinois at Urbana-Champaign [PDF]

, 2007
Computer science is seeing a decline in enrollment at all levels of education, including undergraduate and graduate study. This paper reports on the results of a study conducted at the University of Illinois at Urbana-Champaign which evaluated students ...
Chambers, Erin Wolf, Crenshaw, Tanya L., Metcalf, Heather, Thakkar, Umesh   +3 more
core   +1 more source

Reproducibility and Explainability of Deep Learning in Mammography: A Systematic Review of Literature

Indian Journal of Radiology and Imaging
Background Although abundant literature is currently available on the use of deep learning for breast cancer detection in mammography, the quality of such literature is widely variable.
Deeksha Bhalla, Krithika Rangarajan, Tany Chandra, Subhashis Banerjee, Chetan Arora   +4 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Implementing a One Address CPU in Logisim [PDF]

, 2016
Most computer users have an incorrect, but useful, cognitive metaphor for computers in which the user says (or types or clicks) something and a mystical, almost intelligent or magical, behavior happens.
Kann, Charles W
core   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

PEMETAAN KOMPETENSI INTERNET DOSEN DAN MAHASISWA (Sebuah Penelitian Awal Inisiasi Internet-Assisted Learning di FIK UNY) [PDF]

, 2011
This research aims at exploring the ability levels of lecturers and students of Faculty of Sport Science, Yogyakarta State University, in using the internet as an effort in improving the quality of internet-based instructions to the employment of ...
Nopembri, Soni, Setiawan, Caly
core  

Landscape of K-12 Computer Science Education in the U.S.: Perceptions, Access, and Barriers

Technical Symposium on Computer Science Education, 2016
Through surveys of 1,673 students, 1,685 parents, 1,013 teachers, 9,693 principals, and 1,865 superintendents across the United States, this study explores perceptions, access, and barriers to computer science education at the K-12 level.
Jennifer Wang, Hai Hong, Jason Ravitz, S. H. Moghadam   +3 more
semanticscholar   +1 more source