Results 101 to 110 of about 2,886,954 (299)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
STAR ProtocolsSummary: Spatial transcriptomics enhances our understanding of cellular organization by mapping gene expression data to precise tissue locations. Here, we present a protocol for using weighted ensemble method for spatial transcriptomics (WEST), which ...
Jiazhang Cai +5 more
doaj +1 more source
Periodismo de precisión: el método socioinformático de investigación de la actualidad / The precision journalism: the socio-computer approach of today research [PDF]
Comunicación y Hombre, 2009 El periodismo de precisión es una especialidad, a caballo entre el periodismo de investigación y elperiodismo científico, que permite a los medios de comunicación prestar mayor y mejor atención aproblemas importantes, utilizando métodos adecuados para ...
Homero Valencia Benito
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Who or what was the inspiration for choosing your current course of study? [PDF]
, 2009 Award winning student essay. This essay won the Student Writing Award Scheme via the HE Academy Subject Network for Information and Computer ...
Anantharajan, Mayuran
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Protocol for sequence clustering with PaSiMap in Jalview
STAR ProtocolsSummary: Pairwise similarity mapping (PaSiMap), implemented in Jalview, serves as an alternative to principal component analysis (PCA) for analyzing protein sequence relationships without requiring pre-computed multiple sequence alignments.
Thomas Morell +5 more
doaj +1 more source
, 2015 The 2015 iConference Doctoral Colloquium is made possible in part by a generous grant from the National Science Foundation (#1519338).
University of California. Irvine Donald Bren School of Information and Computer Sciences
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source