Results 131 to 140 of about 2,886,954 (299)

Protocol for visualizing complex volatile metabolomics data in clinical setups using EDaViS software

STAR Protocols
Summary: Here, we present a protocol for using Early Data Visualization Script, a user-friendly software tool to visualize complex volatile metabolomics data in clinical setups.
Leo Ruehrmund, Patricia Fuchs, Julia Bartels, Rasmus Remy, Ann-Christin Klemenz, Nele Kemnitz, Phillip Trefz, Pritam Sukul, Wolfram Miekisch, Jochen K. Schubert   +9 more
doaj   +1 more source

The Logic of the Method of Agent-Based Simulation in the Social Sciences: Empirical and Intentional Adequacy of Computer Programs [PDF]

The classical theory of computation does not represent an adequate model of reality for simulation in the social sciences. The aim of this paper is to construct a methodological perspective that is able to conciliate the formal and empirical logic of ...
Helder Coelho, Jaime Sim�o Sichman, Nuno David   +2 more
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Protocol for performing deep learning-based fundus fluorescein angiography image analysis with classification and segmentation tasks

STAR Protocols
Summary: Fundus fluorescein angiography (FFA) examinations are widely used in the evaluation of fundus disease conditions to facilitate further treatment suggestions. Here, we present a protocol for performing deep learning-based FFA image analytics with
Zhenzhe Lin, Xinyu Zhao, Shanshan Yu, Liqiong Xie, Yue Xu, Lanqin Zhao, Guoming Zhang, Shaochong Zhang, Yan Lu, Haotian Lin, Xiaoling Liang, Duoru Lin   +11 more
doaj   +1 more source

Sources of Male and Female Students' Belonging Uncertainty in the Computer Sciences. [PDF]

Front Psychol, 2019
Höhne E, Zander L.
europepmc   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

XML and computational science

Computing in Science & Engineering, 2004
The Extensible Markup Language (XML) is a specification for document interchange that the World Wide Web Consortium (W3C) developed in 1998. In many ways, XML is the lingua franca among programming language enthusiasts, and proponents argue that it could potentially solve the multitude of data management and analysis problems the entire computing ...
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Computing in Science [PDF]

Science, 1993
openaire   +2 more sources