This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He +10 more
wiley +1 more source
Assessing spider fear: Validity of a novel computerized behavioral avoidance test. [PDF]
Karner A +3 more
europepmc +1 more source
Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun +15 more
wiley +1 more source
Self-efficacy in nutritional care for older adults among hospital-based nurses: a latent profile and network simulation analysis. [PDF]
Wei LZ +4 more
europepmc +1 more source
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li +7 more
wiley +1 more source
A study on user innovative behavior of AI painting tools integrating SOR and Self-Determination theory. [PDF]
Fan L +6 more
europepmc +1 more source
Development of a Digital Multimodal Pain Intervention (CHRONIC): Protocol for a Randomized Controlled Trial Study. [PDF]
Bunjaku G +3 more
europepmc +1 more source
Creative Motivation and Self-Efficacy Moderate the Differences in Individual Creativity Performance in Interactive Situations. [PDF]
Wu CL.
europepmc +1 more source
The effect of gamified breastfeeding education on breastfeeding self-efficacy and ınfant feeding attitudes of pregnant women: a randomized controlled study. [PDF]
Bulut OU, Golbasi Z.
europepmc +1 more source
Improved coping and self-efficacy drive improvements in mood among caregivers of patients with primary malignant brain tumors: Results from a randomized controlled trial. [PDF]
Willis KD +10 more
europepmc +1 more source

