Results 31 to 40 of about 141,473 (262)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Nursing Students’ Computer Self-Efficacy and Attitudes toward Its Use in The Health Care Setting: A Comparative Study

open access: yesEvidence-Based Nursing Research
Context: The use of technology and computers in health care has been reported to improve nurses' decision-making and competencies, which in turn increase the quality of health-care practice.
Farida M. Hassona   +2 more
doaj   +1 more source

The development of an online learning readiness scale for high school students

open access: yesInternational Journal of Assessment Tools in Education, 2022
Assessing students’ online learning readiness is important since numerous countries have started online learning at all education levels during the Covid-19 pandemic in the 21st century.
Ali Çetin   +2 more
doaj   +1 more source

Computer Usage: The Impact of Computer Anxiety and Computer Self-efficacy

open access: yesProcedia - Social and Behavioral Sciences, 2015
AbstractComputer has become an imperative instrument in every organization, particularly in today's era of globalization. However, previous studies indicated that employee still facing problem using the computer due to the rapid changes in computer application.
Achim, Nurˋain, Kassim, Arraqib Al
openaire   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Relationships between middle school students’ digital literacy skills, computer programming self-efficacy, and computational thinking self-efficacy

open access: yesInformatics in Education
This study aims to explain the relationships between secondary school students' digital literacy, computer programming self-efficacy and computational thinking self-efficacy. The study group consists of 204 secondary school students.
Muhammed Murat Gümüş   +2 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

PENGARUH PEMAHAMAN SIKLUS AKUNTANSI PERUSAHAAN DAGANG, INTENSITAS LATIHAN SOAL, DAN COMPUTER KNOWLEDGE TERHADAP HASIL BELAJAR KOMPUTER AKUNTANSI DENGAN SELF-EFFICACY SEBAGAI VARIABEL INTERVENING

open access: yesRefleksi Edukatika
The aim of this research is to determine the influence of understanding the trading company accounting cycle, intensity of practice questions, and computer knowledge on accounting computer learning outcomes and to investigate the indirect influence ...
Suma Manistasari, Agung Listiadi
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Computer Self-efficiency of Pre-service IT Teachers

open access: yesTurkish Journal of Education, 2012
Within FATİH Project, it’s aimed to use information technology more effectively in learning environments and targeted to make technological infrastructure improvements in schools. For this process information technology teachers play a key role.
Mehmet Tekerek   +3 more
doaj  

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