Results 41 to 50 of about 141,473 (262)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Pengembangan Uji Kompetensi Mandiri Berbasis Komputer Untuk Meningkatkan Efikasi Diri Siswa

open access: yesJurnal Pendidikan Fisika Indonesia, 2014
Contoh penerapan teknologi dalam pendidikan adalah Computer Based Testing (CBT). Efikasi diri adalah keyakinan seseorang untuk menyelesaikan tugas. Uji Kompetensi Mandiri merupakan untuk menguji kompetensi siswa secara mandiri.
Sudar -, A. Yulianto, Wiyanto -
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

Postgraduate Students’ Research Self-Efficacy Beliefs and Computer Attitudes

open access: yesGaziantep Üniversitesi Sosyal Bilimler Dergisi, 2010
This study aims to investigate the research self-efficacy beliefs and computer attitudes of post-graduate students. The correlations between the research selfefficacy beliefs and computer attitudes is also measured and it is tried to found out whether ...
Cemalettin İPEK   +2 more
doaj  

THE EFFECT OF COMPUTER SELF-EFFICACY, COMPETENCE, AND WORK ENVIRONMENT ON THE PERFOMANCE OF UNISNU JEPARA EDUCATIONAL STAFF

open access: yesJournal of Management Small and Medium Enterprises (SME's)
This research aims to analyze the effect of computer self-efficacy, competence, and work environment on the performance of UNISNU Jepara educational staff.
Nur Lailatus Shofia, Eko Nur Fu’ad
doaj   +1 more source

Entrepreneurial Intention: The Impact of General Computer Self-Efficacy and Computer Anxiety

open access: yesInteracting with Computers, 2020
Abstract Entrepreneurs are valuable assets because of their enormous contribution to their nations’ economy through creating new ventures and job opportunities. The entrepreneurship literature is informative with respect to what drives individuals to become entrepreneurs.
Mousa Albashrawi, Tawfiq Alashoor
openaire   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

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