Results 61 to 70 of about 1,834,508 (327)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Frontiers in Neuroinformatics, 2017 Gaining a better understanding of the human brain continues to be one of the greatest challenges for science, largely because of the overwhelming complexity of the brain and the difficulty of analyzing the features and behavior of dense neural networks ...
Juan J. Garcia-Cantero +9 more
doaj +1 more source
Scheduling Algorithms for a Hybrid Flow Shop under Uncertainty
Algorithms, 2020 In modern production systems, scheduling problems have to be solved in consideration of frequently changing demands and varying production parameters.
Christin Schumacher, Peter Buchholz
doaj +1 more source
Simulation of chemical reaction dynamics on an NMR quantum computer
, 2011 Quantum simulation can beat current classical computers with minimally a few tens of qubits and will likely become the first practical use of a quantum computer.
C. Zalka +12 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Optimal control strategy of COVID-19 spread in Morocco using SEIRD model
Moroccan Journal of Pure and Applied Analysis, 2021 This paper aims to predict the development of the COVID-19 pandemic in Morocco from a mathematical approach. Based on the reliability of the data and the nature of confirmed cases, the SEIRD model is employed to provide a theoretical framework to ...
Ferjouchia H. +3 more
doaj +1 more source
, 1985 This paper examines the various uses of simulation for education and training which involve the exploitation of the computer for the running of all or part of the simulation. The development of this form of simulation can be seen as a part of the growth in computer based training (CBT) in \ud recent years, which has been given renewed impetus by recent
openaire +1 more source
Phase diagram of silica from computer simulation
, 2004 We evaluate the phase diagram of the ``BKS'' potential [Van Beest, Kramer and van Santen, Phys. Rev. Lett. 64, 1955 (1990)], a model of silica widely used in molecular dynamics (MD) simulations. We conduct MD simulations of the liquid, and three crystals
Francesco Sciortino +6 more
core +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Biotite: new tools for a versatile Python bioinformatics library
BMC Bioinformatics, 2023 Background Biotite is a program library for sequence and structural bioinformatics written for the Python programming language. It implements widely used computational methods into a consistent and accessible package.
Patrick Kunzmann +7 more
doaj +1 more source