Results 71 to 80 of about 2,572,059 (359)

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Harmonic Response Analysis of Tank Design Effect on Ultrasonic Cleaning Process

open access: yesFluids, 2022
Several ultrasonic cleaning tanks (UCTs) had a problem: a manufacturer complained that there were damages to cleaning objects, they were unclarified, and it needed to be abruptly solved.
Suchada Phophayu   +2 more
doaj   +1 more source

Quantum Computation and Quantum Information [PDF]

open access: yesStatistical Science 2012, Vol. 27, No. 3, 373-394, 2012
Quantum computation and quantum information are of great current interest in computer science, mathematics, physical sciences and engineering. They will likely lead to a new wave of technological innovations in communication, computation and cryptography.
arxiv   +1 more source

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

Qdensity - a Mathematica Quantum Computer Simulation

open access: yes, 2005
This Mathematica 5.2 package~\footnote{QDENSITY is available at http://www.pitt.edu/~tabakin/QDENSITY} is a simulation of a Quantum Computer. The program provides a modular, instructive approach for generating the basic elements that make up a quantum ...
Bell   +17 more
core   +2 more sources

From estimation of quantum probabilities to simulation of quantum circuits [PDF]

open access: yesQuantum 4, 223 (2020), 2017
Investigating the classical simulability of quantum circuits provides a promising avenue towards understanding the computational power of quantum systems. Whether a class of quantum circuits can be efficiently simulated with a probabilistic classical computer, or is provably hard to simulate, depends quite critically on the precise notion of "classical
arxiv   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Computer simulation of protein systems [PDF]

open access: yes, 1984
Ligand binding to dihydrofolate reductase (DHFR) is discussed. This is an extremely important enzyme, as it is the target of several drugs (inhibitors) which are used clinically as antibacterials, antiprotozoals and in cancer chemotherapy. DHFR catalyzes
Dauber-Osguthorpe, P.   +4 more
core   +1 more source

Computer simulation of CRS populations

open access: yesCalifornia Agriculture, 1985
California red scale is one of the thre major arthropodpests of citrus in California, causing an anual economic crop los of aproximately $1 5 milion. CRS infestations can lower the market grade of fruit as wel as cause reduced tre vigor and twig and ...
J Morse, M Arbaugh, D Moreno
doaj  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

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