Results 71 to 80 of about 9,192,163 (381)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

A Survey of Ocean Simulation and Rendering Techniques in Computer Graphics [PDF]

, 2011
This paper presents a survey of ocean simulation and rendering methods in computer graphics. To model and animate the ocean's surface, these methods mainly rely on two main approaches: on the one hand, those which approximate ocean dynamics with ...
Adabala, Adams, Arvo, Baboud, Becker, Belyaev, Biesel, Bouws, Bridson, Browing, Bruneton, Carlson, Cerezo, Chen, Chen, Chiu, Chou, Clavet, Cui, Darles, Desbrun, Desbrun, Enright, Fang, Finch, Foster, Foster, Foster, Fournier, Frechot, Frish, Gamito, Gonzato, Gonzato, Gordon, Greenwood, Gutierrez, Harlow, Hasselman, Heckbert, Hinsinger, Holmberg, Hong, Hu, Iglesias, Isidoro, Iwasaki, Iwasaki, Iwasaki, Jensen, Jerlov, Jerlov, Jeschke, Johanson, Kass, Kim, Koshizuka, Kryachko, Lachman, Lee, Lee, Lee, Losasso, Losasso, Losasso, Lucy, Mastin, Max, Mihalef, Miller, Mitchell, Monaghan, Morel, Munk, Müller, Müller, Nishita, O’Brien, Peachey, Perez-Cazorla, Pierson, Premoze, Premoze, Radovitzky, Reeves, Robine, Salgado, Schachter, Schlick, Schneider, Solenthaler, Stam, Stora, Takahashi, Terzopoulos, Tessendorf, Thon, Thon, Thon, Thürey, Thürey, Thürey, Tonnesen, Ts’o, Vincent, Wan, Wang, Wang, Watt, Xin, Yan, Yoon, Yu, Yuksel, Zheng   +114 more
core   +4 more sources

Variational ansatz-based quantum simulation of imaginary time evolution [PDF]

npj Quantum Information, 2018
Imaginary time evolution is a powerful tool for studying quantum systems. While it is possible to simulate with a classical computer, the time and memory requirements generally scale exponentially with the system size.
Sam McArdle, Tyson Jones, Suguru Endo, Ying Li, S. Benjamin, Xiao Yuan   +5 more
semanticscholar   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Computer simulation of a novel pharmaceutical silicon nanocarrier

Nanotechnology, Science and Applications, 2010
Saeed Soltani, Soroush Sardari, Sima Azadi SororDrug Design and Bioinformatics Unit, Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, IranAbstract: We show the potential of the nanosilicon structure of ...
Saeed Soltani, Soroush Sardar, Sima Azadi Soror   +2 more
doaj  

Simulation of chemical reaction dynamics on an NMR quantum computer

, 2011
Quantum simulation can beat current classical computers with minimally a few tens of qubits and will likely become the first practical use of a quantum computer.
C. Zalka, Dawei Lu, Hongwei Chen, J. Baugh, Jiangbin Gong, Jiangfeng Du, M. Shapiro, M. A. Nielson, Nanyang Xu, P. Shor, Ruixue Xu, S. A. Rice, Xinhua Peng   +12 more
core   +1 more source

Toward a first-principles integrated simulation of tokamak edge plasmas [PDF]

, 2008
Performance of the ITER is anticipated to be highly sensitive to the edge plasma condition. The edge pedestal in ITER needs to be predicted from an integrated simulation of the necessary first-principles, multi-scale physics codes.
A Khan, A Kritz, A Pankin, A Shoshani, A Sim, Aymar R, C Docan, C Jin, C Reinhold, C S Chang, Chang C S, D Keyes, D Schultz, D Silver, D Stotler, D Zorin, E D' Azevedo, E Feibush, E Yoon, F Hinton, G Bateman, G Park, Greenwald M, H Abbasi, H Strauss, H Weitzner, J Cummings, J Lofstead, K Bennett, K Schwan, Klasky S, L Greengard, L Sugiyama, Leonard A W, Lofstead J, M Adams, M Nagappan, M Parashar, M Pindzola, M Vouk, M Wolf, N Podhorszki, P Krsti, P Mouallem, P Worley, Park G Y, R Barreto, R Samtaney, S Ethier, S Klasky, S Ku, S Parker, Shoshani A, T Hahm, T Lao, W Lee, Y Chen, Y Xiao, Z Lin   +58 more
core   +1 more source

Computer Simulations [PDF]

, 1985
This paper examines the various uses of simulation for education and training which involve the exploitation of the computer for the running of all or part of the simulation. The development of this form of simulation can be seen as a part of the growth in computer based training (CBT) in \ud recent years, which has been given renewed impetus by recent
openaire   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

An adaptive variational algorithm for exact molecular simulations on a quantum computer [PDF]

Nature Communications, 2018
Quantum simulation of chemical systems is one of the most promising near-term applications of quantum computers. The variational quantum eigensolver, a leading algorithm for molecular simulations on quantum hardware, has a serious limitation in that it ...
Harper R. Grimsley, S. Economou, Edwin Barnes, N. Mayhall   +3 more
semanticscholar   +1 more source