Results 111 to 120 of about 7,984,444 (369)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Software for Quantum Computation

, 2019
Some computational tasks, such as solving the discrete logarithm problem, can be computed with exponential better scaling on quantum computers than using classical hardware. Due to these algorithms, a digital quantum computer is strongly sought after. A scalable quantum computer needs fault-tolerant protocols to correct for errors and deviations due ...
openaire   +3 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Bi-DNE: bilayer evolutionary pattern preserved embedding for dynamic networks

Complex & Intelligent Systems
Network embedding is a technique used to generate low-dimensional vectors representing each node in a network while maintaining the original topology and properties of the network.
Xu Gu, Xiaoliang Chen, Min Yang, Yajun Du, Mingwei Tang   +4 more
doaj   +1 more source

Review of Informing the Future of the Past: Guidelines for Historic Environment Records 2nd edition (website)

Internet Archaeology, 2007
Informing the Future of the Past: Guidelines for Historic Environment Records (second) edition is billed as the 'New and improved manual that empowers HER managers to realise the full potential of their records as information systems for the historic ...
Ben Robinson
doaj   +1 more source

Validation of computer software to estimate dietary intake among patients with type 2 diabetes. [PDF]

J Clin Biochem Nutr, 2021
Wada S, Yamamoto E, Kobayashi Y, Otsuki M, Takada C, Aoi W, Okagaki M, Neriya H, Hamaguchi M, Tanaka M, Fukui M, Higashi A.   +11 more
europepmc   +1 more source

A computer-terminal, hardware/software system with enhanced user input capabilities [PDF]

, 1976
Roy Kaplow, Michael Molnar
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Non rivalry and complementarity in computer software [PDF]

In this paper we contend that – contrary to what argued by a vast part of the literature – computer software and, more in general, digital goods (i.e. symbolic strings on an electronic medium with some eco- nomic value) do not present the characteristics
Marengo, Luigi, Pasquali, Corrado
core   +1 more source

Development of a Collaborative Design Tool for Structural Analysis in an Immersive Virtual Environment [PDF]

, 2001
This paper contains the results of an on-going collaborative research effort by the departments of Architecture and Computer Science of Virginia Polytechnic Institute and State University, U.S.A., to develop a computer visualization application for the ...
Bowman, Doug A., Setareh, M., Tumati, P.
core   +1 more source