Results 121 to 130 of about 3,360,768 (285)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

In the soft-to-hard technical spectrum: Where is software engineering? [PDF]

open access: yes
In the computer journals and tabloids, there have been a plethora of articles written about the software engineering field. But while advocates of the need for an engineering approach to software development, it is impressive how many authors have ...
Leibfried, Theodore F.   +1 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Exploiting Computer Software

open access: yesBond Law Review, 1996
Gordon Hughes
doaj   +1 more source

Dataset for Single Character Detection in Dongba Manuscripts

open access: yesScientific Data
The Dongba script, a unique pictographic writing system invented by the ancestors of the Naxi people of China, holds great significance for interpreting the ancient Naxi language, history, and culture.
Yuqi Ma   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy