Results 61 to 70 of about 7,984,444 (369)

Usability and open source software. [PDF]

open access: yes, 2002
Open source communities have successfully developed many pieces of software although most computer users only use proprietary applications. The usability of open source software is often regarded as one reason for this limited distribution. In this paper
Nichols, David M., Twidale, Michael B.
core   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Optimization of companies’ activity on development of electronic product

open access: yesNauka ta progres transportu, 2012
The article considers modern processes of informatization of activity for business companies. There are generalized the makes of world companies, which create information technologies in global information environment: the electronic information product ...
K.V. Nalivaychenko
doaj  

cisTEM: User-friendly software for single-particle image processing

open access: yesbioRxiv, 2017
We have developed new open-source software called cisTEM (computational imaging system for transmission electron microscopy) for the processing of data for high-resolution electron cryo-microscopy and single-particle averaging.
Tim Grant, A. Rohou, N. Grigorieff
semanticscholar   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Improved CT algorithm based on target block division and feature points matching

open access: yesEURASIP Journal on Image and Video Processing, 2018
For compressive tracking (CT) algorithm, it is vulnerable to the occlusion, when tracking targets. An improved CT algorithm based on target division and feature point matching is proposed in this paper, which can determine different target tracking ...
Wenhao Wang   +4 more
doaj   +1 more source

SISVAR: A COMPUTER ANALYSIS SYSTEM TO FIXED EFFECTS SPLIT PLOT TYPE DESIGNS

open access: yes, 2019
This paper presents a special capability of Sisvar to deal with fixed effect models with several restriction in the randomization procedure. These restrictions lead to models with fixed treatment effects, but with several random errors.
D. F. Ferreira
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

USAGE OF COMPUTERISED MEANS IN VOCAL ASSESSMENT

open access: yesStudia Universitatis Babeş-Bolyai. Musica, 2012
This study investigates implementation of new technologies in vocal assessment pertaining to university degree artistic education. One of our objectives represents the collection of information regarding changes occurring in singing voice as a result of
Ana RUSU
doaj  

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