Results 111 to 120 of about 3,565,684 (300)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 1999 SIGLEAvailable from British Library Document Supply Centre-DSC:m00/13354 / BLDSC - British Library Document Supply CentreGBUnited ...
Randell, B. +2 more
core
Advancing Molecular Spectroscopy Efficiency with Extensive Parallelism
MetrologyMolecular spectroscopy, with a legacy spanning over a century, has profoundly enriched our understanding of the microscopic world, driving major advancements across science and engineering.
Jiaqi Li +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Computers, Learning Outcomes, and the Choices Facing Students [PDF]
We model the tradeoff students face between devoting time to coursework and time for other activities. We show how the model can be used to identify whether computers are productive tools and whether students will learn more when using computers.
Lester Hadsell, Gerald T. Burke
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Growing Molecular Plant Sciences
, 2014 The VT Molecular Plant Sciences Magazine features the work of scientists and students in the department who use molecular approaches to unravel the mysteries of ...
Molecular Plant Sciences +1 more
core
Computers, Skills and Wages [PDF]
Computer use is mainly associated with skilled, high-wage workers. Furthermore, the introduction of computers leads to upgrading of skill requirements.
Weel,B.,ter, Borghans,L.
core +2 more sources
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source