Results 71 to 80 of about 28,142 (308)

Molecular Computing by PNA [PDF]

Artificial DNA: PNA & XNA, 2011
Molecular computing is potentially one of the most powerful tools for the development of massive parallel computing protocols. In the present paper, a first example of the use of PNA:PNA interactions in molecular computing is described. A series of short PNA sequences have been designed with a four base stretch coding for variables and solutions ...
TOTSINGAN, Filibert, MARCHELLI, Rosangela, CORRADINI, Roberto   +2 more
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Comparing Centrifugal And Falling Film Molecular Stills Using Reflux And Cascade For Fine Chemical Separations

, 2015
Molecular distillation is an important separation process that uses high vacuum and low temperatures. The molecular distillation can present, in some cases, reduced power ofseparation using just one stage of distillation.
Batistella C.B., Moraes E.B., WolfMaciel M.R.   +2 more
core   +1 more source

Computation of molecular excited states on IBM quantum computers using a discriminative variational quantum eigensolver [PDF]

, 2020
Solving for molecular excited states remains one of the key challenges of modern quantum chemistry. Traditional methods are constrained by existing computational capabilities, limiting the complexity of the molecules that can be studied or the accuracy ...
Wossnig, L, Grant, E, Tilly, J, Chen, H, Jones, G   +4 more
core  

Evolving artificial cell signaling networks using molecular classifier systems [PDF]

, 2006
Nature is a source of inspiration for computational techniques which have been successfully applied to a wide variety of complex application domains. In keeping with this we examine Cell Signaling Networks (CSN) which are chemical networks responsible ...
James Decraene, McMullin, Barry, Decraene, James, George Mitchell, Mitchell, George G., Barry McMullin   +5 more
core   +1 more source

Large-scale photonic network with squeezed vacuum states for molecular vibronic spectroscopy

Nature Communications
Although molecular vibronic spectra generation is pivotal for chemical analysis, tackling such exponentially complex tasks on classical computers remains inefficient.
Hui Hui Zhu, Hao Sen Chen, Tian Chen, Yuan Li, Shao Bo Luo, Muhammad Faeyz Karim, Xian Shu Luo, Feng Gao, Qiang Li, Hong Cai, Lip Ket Chin, Leong Chuan Kwek, Bengt Nordén, Xiang Dong Zhang, Ai Qun Liu   +14 more
doaj   +1 more source

Ten quick tips for homology modeling of high-resolution protein 3D structures.

PLoS Computational Biology, 2020
The purpose of this quick guide is to help new modelers who have little or no background in comparative modeling yet are keen to produce high-resolution protein 3D structures for their study by following systematic good modeling practices, using ...
Yazan Haddad, Vojtech Adam, Zbynek Heger
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Generating approximate ground states of strongly correlated quantum many-body systems through quantum imaginary time evolution

Journal of Physics Communications
Most quantum algorithms designed to generate or probe properties of the ground state of a quantum many-body system require as input an initial state with a large overlap with the desired ground state.
Michael Kaicher, Florian Dommert, Christopher Wever, Maximilian Amsler, Michael Kühn, QUTAC Material Science Working Group   +5 more
doaj   +1 more source

Hybrid QM/MM Car-Parrinello Simulations of Catalytic and Enzymatic Reactions

CHIMIA, 2002
First-principles molecular dynamics (Car-Parrinello) simulations based on density functional theory have emerged as a powerful tool for the study of physical, chemical and biological systems.
Maria Carola Colombo, Martin Zumstein, Joost VandeVondele, Marialore Sulpizi, Katrin Spiegel, Ute Röhrig, Stefano Piana, Patrick Maurer, Alessandra Magistrato, Alessandro Laio, Leonardo Guidoni, Ursula Röthlisberger   +11 more
doaj   +1 more source