Results 81 to 90 of about 193,488 (294)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Transcriptomic meta-analysis to identify potential antifungal targets in Candida albicans

BMC Microbiology
Background Candida albicans is a fungal pathogen causing human infections. Here we investigated differential gene expression patterns and functional enrichment in C. albicans strains grown under different conditions.
Zeinab Abdelmoghis Hefny, Boyang Ji, Ibrahim E. Elsemman, Jens Nielsen, Patrick Van Dijck   +4 more
doaj   +1 more source

Nonequilibrium molecular dynamics

Condensed Matter Physics, 2005
Nonequilibrium Molecular Dynamics is a powerful simulation tool. Like its equilibrium cousin, nonequilibrium molecular dynamics is based on time-reversible equations of motion. But unlike conventional mechanics, nonequilibrium molecular dynamics provides
Wm.G.Hoover, C.G.Hoover
doaj   +1 more source

Biosensors with Built-In Biomolecular Logic Gates for Practical Applications

Biosensors, 2014
Molecular logic gates, designs constructed with biological and chemical molecules, have emerged as an alternative computing approach to silicon-based logic operations. These molecular computers are capable of receiving and integrating multiple stimuli of
Yu-Hsuan Lai, Sin-Cih Sun, Min-Chieh Chuang   +2 more
doaj   +1 more source

Computer representation of molecular surfaces [PDF]

Journal of Medical Systems, 1982
The recent proliferation of algorithms that produce vector or raster drawings of space-filling models has advanced our understanding of the 3-D structure of molecules.
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Disorder and Motion in Crystal Structures: Nuisance and Opportunities

CHIMIA, 2001
Conventional structure analysis averages the structure of an entire crystal into a single unit cell. If there is disorder and thermal motion, this averaging obscures information on local structure, intermolecular interactions and molecular ...
Hans-Beat Bürgi, Thomas Weber
doaj  

Generating approximate ground states of strongly correlated quantum many-body systems through quantum imaginary time evolution

Journal of Physics Communications
Most quantum algorithms designed to generate or probe properties of the ground state of a quantum many-body system require as input an initial state with a large overlap with the desired ground state.
Michael Kaicher, Florian Dommert, Christopher Wever, Maximilian Amsler, Michael Kühn, QUTAC Material Science Working Group   +5 more
doaj   +1 more source

Towards Understanding the Origin of Genetic Languages

, 2008
Molecular biology is a nanotechnology that works--it has worked for billions of years and in an amazing variety of circumstances. At its core is a system for acquiring, processing and communicating information that is universal, from viruses and bacteria
Patel, Apoorva D.
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source