Results 41 to 50 of about 1,618 (187)

A safety study of high concentration and high frequency intravitreal injection of conbercept in rabbits

open access: yesScientific Reports, 2017
The novel anti-VEGF drug conbercept has been used in the treatment of several retinal neovascular diseases. Owning to the alteration of the structure, the newest drug is capable of combining more molecular targets and present higher affinity to the ...
Jiaming Wang   +6 more
doaj   +1 more source

Predictors of visual recovery in patients with macular edema secondary to central retinal vein occlusion after treatment with Conbercept

open access: yesBMC Ophthalmology, 2021
Background The use of Spectral domain optical coherence tomography (SD-OCT) to evaluate the predictors of visual acuity-recovery in patients treated with conbercept for macular edema (ME) secondary to central retinal vein occlusion (CRVO) has rarely been
Qi Zhang   +8 more
doaj   +1 more source

Comprehensive evaluation of intravitreal conbercept versus half-dose photodynamic therapy for chronic central serous chorioretinopathy [PDF]

open access: yesInternational Journal of Ophthalmology, 2021
AIM: To compare the safety and efficacy of conbercept intravitreal injection and half-dose photodynamic therapy (PDT) in treating chronic central serous chorioretinopathy (CSC). METHODS: This study was retrospective.
Jian-Bo Mao   +9 more
doaj   +1 more source

Intravitreous injection of conbercept for bullous retinal detachment: A case report

open access: yesWorld Journal of Clinical Cases, 2022
Diffuse retinal pigment epitheliopathy (DRPE) associated with bullous retinal detachment is a severe variant of DRPE that is frequently misdiagnosed and often improperly treated.A 36-year-old female patient complained of "painless vision decline in the left eye with obscuration for 10 d".
Xiang, Xiao-Li   +3 more
openaire   +2 more sources

The Role of Intravitreal Anti-VEGF Agents in Rabbit Eye Model of Open-Globe Injury

open access: yesJournal of Ophthalmology, 2021
Purpose. To evaluate the effects of intravitreal anti-VEGF agents in a rabbit model of open-globe injury (OGI). Methods. OGI was induced in the right eyes of 75 Belgian rabbits by making 5 mm circumferential incision placed 6 mm behind the limbus.
Xiao Zhao   +10 more
doaj   +1 more source

Real-world outcomes of two-year Conbercept therapy for diabetic macular edema

open access: goldInternational Journal of Ophthalmology, 2021
AIM: To evaluate the two-year outcomes of patients treated for diabetic macular edema (DME) with intravitreal Conbercept (IVC). METHODS: The clinical data of 30 DME patients (36 eyes) were retrospectively reviewed. The patients were treated with IVC for 3mo. Additional IVC was given at subsequent monthly visits, if needed (3+PRN).
Yong Cheng, Mingwei Zhao, Tong Qian
openalex   +5 more sources

Clinical effect of conbercept on improving diabetic macular ischemia by OCT angiography [PDF]

open access: yesBMC Ophthalmology, 2020
Abstract Background Varying degrees of macular ischemia generally occur in diabetic retinopathy (DR). This study aims to evaluate the effect of conbercept with 3+ pro re nata (PRN) on macular perfusion status in patients with diabetic macular edema (DME) and quantitatively assess changes in ...
Ziyi Zhu   +6 more
openaire   +3 more sources

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov   +8 more
wiley   +1 more source

Comparison of 12-month therapeutic effect of conbercept and ranibizumab for diabetic macular edema: a real-life clinical practice study

open access: yesBMC Ophthalmology, 2017
Background To compare the efficacy of intravitreal conbercept and ranibizumab in the treatment of diabetic macular edema (DME) in a real-life clinical practice. Methods This was a retrospective study.
Yule Xu   +4 more
doaj   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

open access: yesInterdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui   +12 more
wiley   +1 more source

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