Results 51 to 60 of about 1,414 (186)

Predictors of visual recovery in patients with macular edema secondary to central retinal vein occlusion after treatment with Conbercept

BMC Ophthalmology, 2021
Background The use of Spectral domain optical coherence tomography (SD-OCT) to evaluate the predictors of visual acuity-recovery in patients treated with conbercept for macular edema (ME) secondary to central retinal vein occlusion (CRVO) has rarely been
Qi Zhang, Yinfen Hou, Xiao Cao, Rongrong Zhang, Yinping Liu, Chenghua Wei, Changfan Wu, Lixin Mei, Pengfei Zhang   +8 more
doaj   +1 more source

Short-term effects of intravitreal Conbercept injection combined with laser photocoagulation on macular edema secondary to ischemic retinal vein occlusion [PDF]

International Journal of Ophthalmology, 2021
AIM: To observe changes in the best-corrected visual acuity (BCVA), central macular thickness (CMT), and central choroidal thickness (CCT) of patients with macular edema (ME) secondary to ischemic retinal vein occlusion (iRVO) following intravitreal ...
Zheng-Feng Liu, Xing-Rong Wang, Xiao-Yan Zhang, Xue-Mei Pan, Rui-Xue Zhang, Hong-Sheng Bi, Ying Wen   +6 more
doaj   +1 more source

Efficacy and factors associated with reactivation following intravitreal ranibizumab or conbercept for retinopathy of prematurity. [PDF]

Front Med (Lausanne)
PURPOSE: To compare the efficacy of intravitreal ranibizumab (IVR) and conbercept (IVC) treatment for retinopathy of prematurity (ROP) and to evaluate the risk factors associated with disease reactivation.
Liu Q, Li J, Liu J, Xie S, Mu G, Zhao H, Zheng J, Huang X, Wang J.   +8 more
europepmc   +2 more sources

The Role of Intravitreal Anti-VEGF Agents in Rabbit Eye Model of Open-Globe Injury

Journal of Ophthalmology, 2021
Purpose. To evaluate the effects of intravitreal anti-VEGF agents in a rabbit model of open-globe injury (OGI). Methods. OGI was induced in the right eyes of 75 Belgian rabbits by making 5 mm circumferential incision placed 6 mm behind the limbus.
Xiao Zhao, Han Han, Yinting Song, Mei Du, Mengyu Liao, Xue Dong, Xiaohong Wang, Ferenc Kuhn, Annette Hoskin, Heping Xu, Hua Yan   +10 more
doaj   +1 more source

Intraocular pressure effect of intravitreal conbercept injection for retinopathy of prematurity

Frontiers in Pharmacology, 2023
Purpose: Intravitreal injection of conbercept (IVC) is a novel anti-vascular endothelial growth factor (anti-VEGF) treatment for retinopathy of prematurity (ROP). This study aimed to assess the intraocular pressure (IOP) effect of IVC.Methods: All IVC surgeries were performed in the Department of Ophthalmology, Guangdong Women and Children Hospital ...
Caifeng Gao, Ge Mu, Huanhuan Zhao, Jiao Zheng, Qingyang Feng, Yining Wu, Yinan Li, Yinan Li, Xuelin Huang, Wei Sun, Wei Sun   +10 more
openaire   +3 more sources

Multimodal Exploratory Analysis of Persistent Diabetic Macular Edema: Integrating Aqueous Humour Metabolomics, Clinical and OCT Features

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Purpose This exploratory study integrates aqueous humour metabolomic data with clinical and imaging features to examine candidate biomarkers and characterize multimodal patterns associated with persistent diabetic macular edema (pDME). Methods In this prospective cohort study, DME patients were treated with monthly anti‐VEGF injections over 3 ...
Yunhan Tao, Huimin Yu, Yunxi Ma, Mingzhu Yuan, Guochong Chen, Jun Liu, Xi Chen, Xufang Sun   +7 more
wiley   +1 more source

Intravitreous injection of conbercept for bullous retinal detachment: A case report

World Journal of Clinical Cases, 2022
Diffuse retinal pigment epitheliopathy (DRPE) associated with bullous retinal detachment is a severe variant of DRPE that is frequently misdiagnosed and often improperly treated.A 36-year-old female patient complained of "painless vision decline in the left eye with obscuration for 10 d".
Xiang, Xiao-Li, Cao, Yi-Hong, Jiang, Ting-Wang, Huang, Zheng-Ru   +3 more
openaire   +2 more sources

Cascade‐targeted intervention of the NLRP3 inflammasome and downstream angiogenesis by curcumin nanoparticles for ocular neovascularization therapy

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Ultrasound‐microreactor synthesizes monodisperse 125 nm Cur‐NPs with enhanced solubility. Cur‐NPs suppress VEGF signaling and retinal neovascularization via the NLRP3 axis. Multi‐omics profiling reveals that Cur‐NPs reprogram retinal microglia and metabolic pathways.
Siyu Jiang, Ziwei Cheng, Yujuan Cai, Yanji Zhu, Nyamjargal Nyambayar, Ruijie Lin, Li Zhang, Jian Chen, Bing Xie, Xiuping Chen   +9 more
wiley   +1 more source

Schematic structure of conbercept.

, 2013
VEGF receptor-1 and receptor-2 are related receptors that have seven extracellular Ig domain plus an intracellular tyrosine kinase domain. Conbercept contains the Ig domain 2 of VEGF receptor-1 fused to the Ig domain 3 and 4 of VEGF receptor-2 fused to ...
Qin Wang (109812), Quan Wu (444646), Delun Luo (385182), Hui Wang (30400), Tao Li (86810), Zhigang Wu (385181), Xiao Ke (385184)   +6 more
core   +1 more source

Clinical efficacy and acceptability of panretinal photocoagulation combined with conbercept for patients with proliferative diabetic retinopathy: A protocol for systematic review and meta-analysis

, 2022
Although conbercept has been used for other diseases associated with new vascular formation, the effect of single-dose conbercept in combination with proliferative diabetic retinopathy (PDR) have not been established.
Xiaoxue Wang
core   +1 more source