Results 91 to 100 of about 73,159 (258)

The effect of nuclear transcriptional factor κВ activation inhibitor – curcumine on the experimental immune liver disease

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2010
Aim of investigation. To study at two models of immune hepatitis (Т-cellular and antibody origin) in mice damage of the liver, activity and destruction of its immunocompetent cells, thymus gland and the spleen, as well as the effect of curcumine ...
I. N. Alekseyeva, N. V. Makogon, S. I. Pavlovich, T. M. Bryzgina, L. I. Aleksyuk, T. V. Martynova, V. S. Sukhina   +6 more
doaj  

Association of T‐Cell Profiles With Disease Severity, Drug‐Induced Liver Injury, and Treatment Completion in Tuberculosis

The Clinical Respiratory Journal, Volume 19, Issue 8, August 2025.
Fourteen T cell phenotypes were associated with disease severity, including the number of pulmonary cavities. Five T cell phenotypes were associated with drug‐induced liver injury (DILI). The 4‐month and 6‐month treatment groups showed a significant difference in IFN‐γ+ naïve CD8+ T cells at week 16 but not at treatment completion.
Yifan He, Xubin Zheng, Zihan Dang, Xiaohui Hao, Yidian Liu, Peng Wang, Yingying Chen, Ying Wang, Wei Sha   +8 more
wiley   +1 more source

Subpopulations of liver coated vesicles resolved by preparative agarose gel electrophoresis. [PDF]

, 1986
Rat liver clathrin coated vesicles (CVs) were separated into several distinct subpopulations using non-sieving concentrations of agarose, which allowed the separation of species differing primarily in surface charge.
Hill, DF, Kedersha, NL, Kronquist, KE, Rome, LH   +3 more
core  

Flavopiridol Protects Against Inflammation by Attenuating Leukocyte-Endothelial Interaction via Inhibition of Cyclin-Dependent Kinase 9 [PDF]

, 2011
Objective: The cyclin-dependent kinase (CDK) inhibitor flavopiridol is currently being tested in clinical trials as anticancer drug. Beyond its cell death–inducing action, we hypothesized that flavopiridol affects inflammatory processes.
Berberich, Nina, Fürst, Robert, Joore, Jos, Khandoga, Alexander G., Krombach, Fritz, Mayer, Bettina A., Sass, Gabriele, Schmerwitz, Ulrike K., Tiegs, Gisa, Totzke, Frank, Vollmar, Angelika M., Zahler, Stefan   +11 more
core   +1 more source

A Modular Solid Phase Synthesis Approach for Glycocalix[4]Arene Derivatives and Their Multivalent Presentation on Ultrasmall Gold Nanoparticles.

Chemistry – A European Journal, Volume 31, Issue 40, July 17, 2025.
In this study, we present a calix[4]arene building block suitable for modular solid‐phase polymer synthesis and the preparation of functional glycocalix[4]arene. This allows us to incorporate carbohydrate ligands and further functionalities, such as alkynes at a specific position at the upper or lower rim of the calix[4]arene as demonstrated for the ...
Alisa Kayser, Kai Klein, Daria Babushkina, Anne Sakse, Gisele Mouafo Kenne, Ulla I.M. Gerling‐Driessen, Monir Tabatabai, Matthias Epple, Laura Hartmann   +8 more
wiley   +1 more source

Isolation and characterization of a laminin-binding protein from rat and chick muscle. [PDF]

, 1988
A major laminin-binding protein (LBP), distinct from previously described LBPs, has been isolated from chick and rat skeletal muscle (Mr 56,000 and 66,000, respectively).
Frazer, KA, Hall, DE, Hann, BC, Reichardt, LF   +3 more
core  

Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles [PDF]

, 2008
Short interfering RNA (siRNA) attracts much attention for the treatment of various diseases. However, its delivery, especially via systemic routes, remains a challenge. Indeed, naked siRNAs are rapidly degraded, while complexed siRNAs massively aggregate
De Smedt, Stefaan, Demeester, Jo, Lentacker, Ine, Sanders, Niek, Vandenbroucke, Roosmarijn   +4 more
core   +1 more source

Adenine Nucleotides Attenuate Murine T Cell Activation Induced by Concanavalin A or T Cell Receptor Stimulation

Frontiers in Pharmacology, 2018
Extracellular ATP and its metabolites affect various cellular immune responses, including T cell function, but there are apparently conflicting reports concerning the effects of adenine nucleotides on T cells.
Yuria Shinohara, Mitsutoshi Tsukimoto
doaj   +1 more source

Responsive glyco-poly(2-oxazoline)s: synthesis, cloud point tuning, and lectin binding [PDF]

, 2011
A new sugar-substituted 2-oxazoline monomer was prepared using the copper-catalyzed alkyne-azide cycloaddition (CuAAC) reaction. Its copolymerization with 2-ethyl-2-oxazoline as well as 2-(dec-9-enyl)-2-oxazoline, yielding well-defined copolymers with ...
Adams N., Ambrosi M., Aoi K., Aoi K., Aoi K., Aoi K., Bassiri T. G., Bloksma M. M., Campos L. M., Cesana S., Christine Weber, Christova D., Collins B. E., Cortez M. A., Diehl C., Dimick S. M., Gabius H. J., Hoogenboom R., Hoogenboom R., Huber S., Kagiya T., Kempe K., Kempe K., Knop K., Kobayashi S., Kobayashi S., Kobayashi S., Kristian Kempe, Krzysztof Babiuch, Lambermont-Thijs H. M. L., Lin P. Y., Lundquist J. J., Michael Gottschaldt, Mikata Y., Narain R., Richard Hoogenboom, Saegusa T., Saegusa T., Seeliger W., Slavin S., Stillman B. N., Takasu A., Taubmann C., Ting S. R. S., Tomalia D. A., Tsutsumiuchi K., Ulrich S. Schubert, Vazquez-Dorbatt V., Weber C., Wiesbrock F., Wiesbrock F., Witte H.   +51 more
core   +2 more sources

Concanavalin A Toxicity: Histological Studies

Experimental Biology and Medicine, 1976
SummaryCon A injected iv in doses of 200-600 μg produced vascular endothelial damage, hepatic necrosis, and lymphoid atrophy.
Nopanitaya, W, Hanker, J, Tyan, M
openaire   +3 more sources