Results 101 to 110 of about 118,548,475 (188)
Dynamic Combinatorial Carbohydrate Libraries: Probing the Binding Site of the Concanavalin A Lectin
Dynamic combinatorial chemistry (DCC) has emerged as an efficient approach to receptor/ligand identification based on the generation of combinatorial libraries by reversible interconversion of the library constituents.
Taridaporn Bunyapaiboonsri +7 more
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DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang +7 more
wiley +1 more source
Liver’s contribution to innate immunity is eminent. However, uncontrolled inflammatory conditions predispose the liver to immune-mediated injury. Nigella sativa L.
Aqsa Mushtaq +7 more
doaj +1 more source
This review firstly summarizes the update of meroterpenoids from February 2020 to December 2025 by applying a new classification method based on twelve key non‐terpene precursors. ABSTRACT Meroterpenoids are a class of hybrid natural products, biosynthesized from terpenoid fragments and non‐terpenoid precursors, exhibiting a wide range of biological ...
Yuqian Tang +6 more
wiley +1 more source
γ‐T3 Increases the Sensitization of Gastric Cancer Cells to OXA by a Regulation of ARHGAP29
γ‐T3 combined with oxaliplatin (OXA) inhibited the proliferation of gastric cancer cells by induction autophagy via ARHGAP29/GSK‐3β/β‐Catenin pathways. γ‐T3 combined with low‐dose of OXA could exert synergistic effects on induction autophagy‐related gastric cancer cell death, which is partially mediated by down‐regulation of the ARHGAP29/GSK‐3β/β ...
Hao Zhu +11 more
wiley +1 more source
Citation: 'concanavalin A' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13034 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Bacterial sialidases subvert the complement system through desialylation
Abstract Bacterial sialidases (neuraminidases) are widely studied virulence factors, yet their impact on the complement system, a central component of innate immunity, remains poorly understood. Here, we investigate the effects of six sialidases from five human pathogens, including Bacteroides fragilis, Clostridium perfringens, Tannerella forsythia ...
Kurni Kurniyati +6 more
wiley +1 more source
Type‐V myosin (Myo2) promotes the motion of Mps3 patches on the nuclear membrane during yeast meiosis. On the other hand, Sac6 fimbrin, which bundles actin filaments, is not critical for the motion of Mps3, suggesting the role of a few actin filaments in the Mps3 motion.
Shuangping Cheng +4 more
wiley +1 more source
Hydrogen sulfide, a potential novel drug, attenuates concanavalin A-induced hepatitis
Ping Cheng,* Kan Chen,* Yujing Xia, Weiqi Dai, Fan Wang, Miao Shen, Chengfen Wang, Jing Yang, Rong Zhu, Huawei Zhang, Jingjing Li, Yuanyuan Zheng, Junshan Wang, Yan Zhang, Jie Lu, Yingqun Zhou, Chuanyong GuoDepartment of Gastroenterology, Shanghai Tenth ...
Xia Y +16 more
core
Protective effect of galangin in Concanavalin A- induced hepatitis in mice
Qingqiong Luo,1,* Liping Zhu,1,* Jieying Ding,1 Xing Zhuang,1 Lili Xu,2 Fuxiang Chen1 1Department of Clinical Immunology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, 2Division of Gastroenterology, Zhongshan ...
Xu L +5 more
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