Results 101 to 110 of about 65,297 (230)

A novel case of autosomal recessive CARD11 loss‐of‐function underlying impaired antiviral immunity and a review of literature

Clinical &Translational Immunology, Volume 15, Issue 5, 2026.
We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson, Cecilia Verryt, Paula Keating, Thomas Saunders, Samuel Dalton, Barry D Hock, Liping Goddard, Kylie Drake, Anja Werno, John O'Donnell, Jeffrey R Stinson, Andrew L Snow, Kuang‐Chih Hsiao   +12 more
wiley   +1 more source

Effect of cholesterol nucleation-promoting activity on cholesterol solubilization in model bile.

Journal of Lipid Research, 1989
Human bile contains a factor with cholesterol nucleation-promoting activity that binds to concanavalin A-Sepharose. In this study we have investigated the effect of this activity on the dynamics of lipid solubilization in supersaturated model bile.
A K Groen, R Ottenhoff, P L Jansen, J van Marle, G N Tytgat   +4 more
doaj   +1 more source

Effect of floor type on the performance, physiological and behavioural responses of finishing beef steers [PDF]

, 2015
peer-reviewedBackground:The study objective was to investigate the effect of bare concrete slats (Control), two types of mats [(Easyfix mats (mat 1) and Irish Custom Extruder mats (mat 2)] fitted on top of concrete slats, and wood-chip to simulate deep ...
A O’Loughlin, AD Fisher, AD Fisher, AWMV Silva De, B Earley, B Earley, B Earley, B Earley, Barry McDonnell, Bernadette Earley, C Bergsten, C Bergsten, C Rouha-Muelleder, D Fraser, D Fraser, D Fraser, D Fraser, D Fraser, D Fraser, D Owens, DE Lowe, DJ Mellor, DM Broom, DM Broom, Edward G. O’Riordan, EFSA, EFSA, EFSA, EM Lynch, G Cozzi, GB Scott, H Irps, H Murata, H Schulze Westerath, I Veissier, J Hannan, J Hultgren, J Rushen, J Vanegas, JA Fregonesi, JH Britt, JNA Tilley, KE Schütz, KE Schütz, KL Graunke, KR Buckham Sporer, L Désiré, M Mazurek, MJ Hotzel, ML Jones, MRP Elmore, OM Radostits, PD Eckersall, PR Greenough, PV Kremer, S Gupta, TM Hill   +56 more
core   +1 more source

Adapted Live SARS‐CoV‐2 Vaccine Elicits Rapid Mucosal Immunity, Protects From Disease, and Reduces Shedding of XBB.1.5

European Journal of Immunology, Volume 56, Issue 5, May 2026.
An attenuated live vaccine (OTS‐300) expressing the XBB.1.5 Spike provided rapid and complete protection against homologous challenge in the hamster model, accompanied by fast systemic and mucosal antibody responses and markedly reduced transmission compared with XBB.1.5 mRNA vaccination.
Jana Kochmann, Tobias Britzke, Nico Joël Halwe, Lorenz Ulrich, Angele Breithaupt, G. Tuba Barut, Nadine Ebert, Bettina Salome Trüeb, Volker Thiel, Anca Dorhoi, Martin Beer, Donata Hoffmann, Björn Corleis, Jacob Schön   +13 more
wiley   +1 more source

YTHDF1 shapes immune-mediated hepatitis via regulating inflammatory cell recruitment and response

Genes and Diseases
Severe immune responses regulate the various clinical hepatic injuries, including autoimmune hepatitis and acute viral hepatitis. N6-methyladenosine (m6A) modification is a crucial regulator of immunity and inflammation.
Hao Li, Kailun Yu, Xiandan Zhang, Jiawen Li, Huilong Hu, Xusheng Deng, Siyu Zeng, Xiaoning Dong, Junru Zhao, Yongyou Zhang   +9 more
doaj   +1 more source

Sustained Effector Functions and Memory Accumulation of αβ T Cells in Children With Congenital Heart Disease

European Journal of Immunology, Volume 56, Issue 5, May 2026.
This study showed dysregulated αβ T cell homeostasis with ongoing T cell activation and low‐grade inflammation in 5‐12‐year‐old CHD children who underwent early‐life cardiac surgery with thymectomy, characterized by reduced naïve T cells and increased memory/effector and senescent‐like T cells.
Yusuf Eshimutu Abu, Christoph Kammeyer, Tao Yang, Rodrigo Gutierrez Jauregui, Alexa Cramer, Claudia Junge, Svea Kleiner, Anika Janssen, Adan Chari Jirmo, Alexander Horke, Reinhold Förster, Philipp Beerbaum, Martin Boehne, Sarina Ravens   +13 more
wiley   +1 more source

Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury. [PDF]

, 2019
Animal studies have demonstrated beneficial effects of therapeutic hypothermia on myocardial function, yet exact mechanisms remain unclear. Impaired autophagy leads to heart failure and mitophagy is important for mitigating ischemia/reperfusion injury ...
Andres, Allen M, Crupi, Annunziata, Czer, Lawrence S, Esmailian, Fardad, Gottlieb, Roberta A, Hou, Jean, Marek-Iannucci, Stefanie, Mentzer, Robert M, Sin, Jon, Taylor, David J, Thomas, Amandine   +10 more
core  

Immune‐Enhancing Effects of IBP35, a Combination of Lactiplantibacillus plantarum and Ligilactobacillus salivarius, in Macrophages and Cyclophosphamide‐Induced Immunosuppressed Mice

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
IBP35, a combination of Lactiplantibacillus plantarum IDCC 3501 and Ligilactobacillus salivarius IDCC 3551, enhanced macrophage activation in RAW 264.7 cells and improved multiple immune readouts in cyclophosphamide‐induced immunosuppressed mice, including splenocyte proliferation, NK cell activity, cytokine production, macrophage phagocytic activity ...
Han Bin Lee, Jinho Lee, Kyuho Jeong, Young Hoon Jung, Jin Seok Moon   +4 more
wiley   +1 more source

Unlocking the Hepatoprotective Potential of Cyperus rotundus Through Edible Vinegar Processing: A Study on Functional Ingredient Enhancement

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Cyperus rotundus L. (CR) and vinegar‐processed CR (VCR) were compared in mouse models of thioacetamide (TAA)‐induced acute and chronic liver injury. VCR exhibited better hepatoprotective effects than raw CR. Composition analysis revealed 35 components in VCR, among which α‐cyperone was present at higher levels than in raw CR.
Gao Jia‐He, Lin Li‐Ting, Liu Yue‐Han, Wang Fu‐Chao, Liu Jun‐Tong, Gao Tian‐Hui   +5 more
wiley   +1 more source

Modulation of human lymphocyte function by C3a and C3a(70-77). [PDF]

, 1982
Human C3a and the synthetic octapeptide C3a (70-77), which retains the activities of an anaphylatoxin, inhibit in a concentration-dependent manner the generation of leukocyte inhibitory factor (LIF) activity by human mononuclear leukocytes and T ...
Goetzl, EJ, Payan, DG, Trentham, DE
core