A tri-protein bio-interphase composed of concanavalin A (Con A), cytochrome c (Cyt c) and horseradish peroxidase (HRP) was developed by layer-by-layer assembly of HRP, Con A, mixture of Cyt c and HRP.
Yonghai Song +3 more
doaj +1 more source
Strain-dependent porcine circovirus type 2 (PCV2) entry and replication in T-lymphoblasts [PDF]
Porcine circovirus type 2 (PCV2) is the etiological agent of PCV2-associated diseases (PCVAD). PCV2 targets lymphoblasts, and pigs suffering from PCVAD display lymphocyte depletion in lymphoid tissues. PCV2 infection of lymphoblasts has not been studied.
Nauwynck, Hans +2 more
core +1 more source
Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu +4 more
wiley +1 more source
Controlled method of reducing electrophoretic mobility of macromolecules, particles, or cells [PDF]
A method of reducing electrophoretic mobility of macromolecules, particles, cells, and other substances is provided which comprises interacting in a conventional electrophoretic separating procedure, the substances with a polymer-linked affinity compound
Vanalstine, James M.
core +1 more source
Selective inhibition of T suppressor-cell function by a monosaccharide [PDF]
Interactions between regulatory T lymphocytes and other cells are assumed to occur at the level of the cell surface. T cells which suppress the generation of specifically effector cells have been described as having antigenic, idiotypic, allotypic and I ...
AA Moscona +22 more
core +1 more source
Induction of IL‐9‐producing CD8+ T cells by ascochlorin derivatives
A newly synthesised ascochlorin derivative, N184, induces small amounts of IL‐9‐producing CD8+ T cells. N184 improved the survival of CD8+ T cells and enhanced their antitumour activity, partially in an IL‐9‐dependent manner. The antitumour effect was completely dependent on IFNγ secretion rather than the cytotoxic activity of CD8+ T cells.
Natsumi Imano +5 more
wiley +1 more source
Derangements of liver tissue bioenergetics in Concanavalin A-induced hepatitis
Background A novel in vitro system was employed to investigate liver tissue respiration (mitochondrial O2 consumption) in mice treated with concanavalin A (Con A).
Al-Shamsi Mariam +3 more
doaj +1 more source
Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei [PDF]
Trypanosoma brucei expresses a diverse repertoire of N-glycans, ranging from oligomannose and paucimannose structures to exceptionally large complex N-glycans.
Acosta-Serrano +60 more
core +3 more sources
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam +3 more
core +3 more sources

