Results 141 to 150 of about 118,548,475 (188)

Effect of concanavalin A and succinyl concanavalin A on cytomegalovirus replication in fibroblasts

Archives of Virology, 1986
In order to investigate inhibition of viral replication, human embryonic fibroblasts infected with cytomegalovirus (CMV) were treated with 0 to 25 micrograms/ml concanavalin A (Con A) and 0 to 150 micrograms/ml succinylated Con A (S-Con A). Alterations in cellular morphology occurred by day 2 post infection (p.i.) in cultures treated with 10 micrograms/
A, Grail, M, Norval
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Traffic and assembly of concanavalin A

Trends in Biochemical Sciences, 1988
Abstract Concanavalin A (ConA) is synthesized and packaged into protein bodies during jackbean development. Recent results have shown that traffic of proteins within the plant cells can be disrupted by monensin, when lectin precursors are mis-routed to the cell surface instead of targeted to their correct intracellular destination.
D J, Bowles, D J, Pappin
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The interaction of platelets and concanavalin A

Thrombosis Research, 1975
Abstract The interaction of agglutinating concanavalin A and non-agglutinating trypsinized concanavalin A preparations with platelet surfaces was monitored by determining the gel electrophoretic labelling pattern of platelet membrane protein obtained from iodinated cells pre-incubated with the plant lectin.
K L, Kaplan, R L, Nachman
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Molecularly Imprinted Cryogel Columns for Concanavalin a Purification From Jack Bean Extract

Separation Science Plus, 2018
Concanavalin A, one of most studied lectins for the purification of glycoproteins and sugars, is selected as a model protein. In this study, a Concanavalin A imprinted poly(hydroxyethyl methacrylate) supermacroporous cryogel was prepared for the ...
Adil Denizli, Nilay Bereli, Duygu Çimen
exaly   +2 more sources

The luminescence properties of concanavalin A

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1975
1. The luminescence properties of native concanavalin A, both at room temperature and at 77 degrees K, are similar to those of other proteins containing tyrosine and tryptophan. 2. Binding of methyl alpha-D-glucopyranoside to concanavalin A causes a slight reduction of its fluorescence at room temperature. 3.
J N, Miller, G I, Nwokedi
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Immunosuppressive Activity of Concanavalin A

International Archives of Allergy and Applied Immunology, 2009
Daily intraperitoneal doses of concanavalin A (Con A) produced a dose-related inhibition of adjuvant-induced arthritis in rats. Con A was also effective on established arthritis, markedly relieving the disease after only three doses. The inhibitory effect of Con A was neutralised by pre-incubation with ovalbumin, although this treatment did not modify ...
A K, Delitheos, G B, West
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Concanavalin A as a carrier of daunomycin

Nature, 1977
ONE possible approach for increasing the effectiveness of anti-tumour drugs would be to find methods of altering their distribution in the body to increase their local concentration at the tumour cell sites. Ghose et al. have reported the suppression of Ehrlich ascites carcinoma in mice after administration of chlorambucil allegedly bound to anti ...
Kitao, T, Hattori, K
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Concanavalin A: An Introduction

1975
During the last quarter of the nineteenth century and in the beginning of the twentieth century, bacteriologists were searching for agglutinins which could be used as antibacterial agents. Field and Teague (1907), for example, were working with typhoid agglutinins. Kolmer (1923) was working with various other types of antibacterial agglutinins.
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Agglutination of an Arbovirus by Concanavalin A

Nature New Biology, 1971
MANY enveloped viruses contain carbohydrates as components of glycoproteins1–5 or glycolipid6. We have found (unpublished results) that the envelope of Semliki Forest virus (SFV), a group A arbovirus, contains a glycoprotein in which the principal sugars are mannose, galactose and N-acetylglucos-amine and also a glucose-containing glycolipid.
J D, Oram, D C, Ellwood, G, Appleyard, J L, Stanley   +3 more
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Modification of the Biological Activities of Concanavalin A by Anti-Concanavalin A

1975
Concanavalin A (Con A) bound to cell membrane glycoproteins, may be dissociated from the membrane receptors by competitive ligands such as alpha-methyl-D-mannoside. Addition of antibody to Con A to the system forms complexes of antibody and Con A which are still bound to the membrane receptors.
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