Results 151 to 160 of about 75,255 (281)

Enhancer Rewiring Orchestrates Inflammation and Loss of Cell Identity During Muscle Stem Cell Aging

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
A comprehensive multi‐omic profiling of murine muscle stem cells across three ages and both sexes reveals extensive enhancer and 3D genome rewiring, concomitant with increased inflammation, lineage drift, loss of quiescence, and reduced myogenic potential.
Changyou Shi   +17 more
wiley   +1 more source

Characterization of substance P receptors partially purified by concanavalin A-sepharose from the rat brain

open access: diamond, 1990
Hiroyuki Takamatsu   +3 more
openalex   +1 more source

Small Extracellular Vesicles From Human Amniotic Membrane Mesenchymal Stem Cells Rejuvenate Senescent β Cells and Cure Age‐Related Diabetes in Mice

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
hAMSC‐sEVs rejuvenate β cells and improve glycaemic control via the miR‐21‐5p/IL‐6RA/STAT3/MCU axis, restoring mitochondrial Ca2+ homeostasis and insulin secretion in aged T2DM mice. ABSTRACT Targeting senescent pancreatic β‐cells represents a promising therapeutic avenue for age‐related diabetes; however, current anti‐senescence strategies often ...
Lei Xiao   +8 more
wiley   +1 more source

Spatial Reorganization of Chromatin Architecture Shapes the Expression Phenotype of Therapy‐Induced Senescent Cells

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
In the course of TIS, cells undergo a profound epigenomic reorganization that underlies the development of a senescence‐associated phenotype and formation of an inflammatory microenvironment. ABSTRACT Cellular senescence is a fundamental biological process contributing to aging, often accompanied by extensive chromatin remodeling.
Ge Zhang   +8 more
wiley   +1 more source

Chemical and Mössbauer spectroscopic evidence that iron-containing concanavalin A is a ferritin.

open access: hybrid, 1988
J. Yariv   +5 more
openalex   +1 more source

Structural insights into how vacuolar sorting receptor recognizes the C‐terminal sorting determinant of a vicilin‐like seed storage protein

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 257-270, January 2026.
Soluble cargo proteins are sorted to the vacuoles via a receptor‐mediated mechanism. Combining crystallographic and mutagenesis studies, we showed how the C‐terminal sorting determinant (ctVSD) of vicilin‐like seed storage protein VL22 is recognized by the protease‐associated domain of Arabidopsis vacuolar‐sorting receptor 1.
Shu Nga Lui   +4 more
wiley   +1 more source

Chromosome‐level genome assembly of the photobiont microalga Trebouxia sp. ‘A48’ from the lichen Xanthoria parietina

open access: yesNew Phytologist, Volume 249, Issue 2, Page 1036-1052, January 2026.
Summary Lichens are symbiotic assemblies consisting of multiple organisms, chiefly a fungus and a photosynthetic microorganism, or photobiont. Among diverse photobionts, the most prevalent is the chlorophyte alga Trebouxia. We produced a chromosome‐level assembly of Trebouxia sp. ‘A48’, a photobiont of Xanthoria parietina. The genome was assembled into
Gulnara Tagirdzhanova   +2 more
wiley   +1 more source

Risks for human health related to the presence of plant lectins in food

open access: yesEFSA Journal, Volume 24, Issue 1, January 2026.
Abstract The European Commission asked the European Food Safety Authority (EFSA) to assess the risk related to the presence of plant lectins in food. Based on the available evidence, the CONTAM Panel considered only phytohaemagglutinin (PHA), a legume lectin from beans (Phaseolus sp.), for the risk characterisation.
EFSA Panel on Contaminants in the Food Chain (CONTAM)   +30 more
wiley   +1 more source

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