Results 181 to 190 of about 5,520 (275)

Stafib‐2‐CR: an Improved Nanomolar and Selective Inhibitor of the Transcription Factor STAT5b Developed by Conformational Restriction of Stafib‐2

open access: yesChemistry – A European Journal, EarlyView.
Conformational restriction strategies to increase the activity and selectivity of the STAT5b inhibitor Stafib‐2 are presented. The best conformationally restricted inhibitor Stafib‐2‐CR has threefold higher activity against STAT5b than Stafib‐2. A cell‐permeable prodrug of Stafib‐2‐CR inhibits phosphorylation of STAT5b in cultured human leukemia cells ...
Theresa Münzel   +5 more
wiley   +1 more source

Resolving a Nearly Two‐Centuries‐Old Mystery: On the Structural Chemistry and Physicochemical Properties of Compounds Associated With the Term Ammelide

open access: yesChemistry – A European Journal, EarlyView.
The crystal structure of ammelide, also known as melanuric acid, was solved almost 200 years after its discovery by Liebig. Moreover, three modifications of its 1:1 adduct with ammeline were structurally elucidated, consisting of layers with a honeycomb motif analogous to melamine cyanurate.
Thaddäus J. Koller   +8 more
wiley   +1 more source

Data justice and data solidarity. [PDF]

open access: yesPatterns (N Y), 2022
Braun M, Hummel P.
europepmc   +1 more source

In Situ Methanation on Mars: A Process Concept Study on the Impact of H2/CO2 and Recycle Ratio

open access: yesChemie Ingenieur Technik, EarlyView.
The rocket propellant methane can be produced on Mars by in situ resource utilization. The H2/CO2 ratio is decisive, and excess H2 is favored for providing sufficient propellant purity. The operation mode—with or without recycling of unreacted reactants—depends on the resource availability of the selected landing site. Abstract For return missions from
Franz Braun   +4 more
wiley   +1 more source

Digital learning of clinical skills and its impact on medical students' academic performance: a systematic review. [PDF]

open access: yesBMC Med Educ
McGee RG   +6 more
europepmc   +1 more source

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