Results 51 to 60 of about 12,215,662 (215)

Effect of tube cooling on the osteogenic activity of concentrated platelet-rich fibrin in human periodontal ligament cells

Biomaterial Investigations in Dentistry
Objective: To compare the effect of concentrated platelet-rich fibrin (C-PRF) immediately after collection to C-PRF kept in a cooling device for about 90 min on the proliferation, osteogenic differentiation, and mineralization in human periodontal ...
Rucha Shah, Mavinakote Gowda Triveni, Baron Tarun Kumar, Raison Thomas, Hiral Karwa   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Impact of concentrated growth factor (CGF) injection on acceleration of orthodontic tooth movement in rabbits

BMC Oral Health
Background The present study aimed to assess how a concentrated growth factor (CGF) injection affects the rate of orthodontic tooth movement in rabbits. Methods This experimental investigation employed a split-mouth configuration.
Safa B. Alawy, Mona Al Ahmady El Meligy, Eman M. Salem, Wafaa Yahia Alghonemy   +3 more
doaj   +1 more source

Clinical effect of concentrated growth factors coating in the treatment of stable segmental vitiligo with autologous epidermal transplantation

Pifu-xingbing zhenliaoxue zazhi, 2022
Objective To evaluate the effect and adverse effects of concentrated growth factors coating in the treatment of stable segmental vitiligo with autologous epidermal transplantation.
Feixiang FAN, Zhen HUANG, Zhanying HOU, Po LIU   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The Impact of Two Platelet Concentrates on Healing of Surgically Created Bone Defects in Sheep (Radiological Analysis) [PDF]

Al-Rafidain Dental Journal
The present study aims to assess the density of bone with Concentrated growth factors and advanced plasma-rich fibrin in the bone defects that were created surgically in the sheep’s mandible by the use of radiographic assessment.
Amina Abdolfattah Humadi, Rayan Salim Hamed, Hayam Nori Awad   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source