Results 91 to 100 of about 33,308 (294)

Uniform Continuity and Br\'ezis-Lieb Type Splitting for Superposition Operators in Sobolev Space [PDF]

, 2016
Using concentration-compactness arguments we prove a variant of the Brezis-Lieb-Lemma under weaker assumptions on the nonlinearity than known before.
Ackermann, Nils
core  

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Ground state solutions for asymptotically periodic Schrodinger equations with critical growth

Electronic Journal of Differential Equations, 2013
Using the Nehari manifold and the concentration compactness principle, we study the existence of ground state solutions for asymptotically periodic Schrodinger equations with critical growth.
Hui Zhang, Junxiang Xu, Fubao Zhang
doaj  

Doubly Critical Problems Involving Fractional Laplacians in ℝN

Advanced Nonlinear Studies, 2017
In this paper, we show the existence of nontrivial solutions for doubly critical nonlocal elliptic problems in ℝN{\mathbb{R}^{N}} involving fractional Laplacians.
Yang Jianfu, Wu Fengjie
doaj   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Existence for (p, q) critical systems in the Heisenberg group

Advances in Nonlinear Analysis, 2019
This paper deals with the existence of entire nontrivial solutions for critical quasilinear systems (𝓢) in the Heisenberg group ℍn, driven by general (p, q) elliptic operators of Marcellini types.
Pucci Patrizia, Temperini Letizia
doaj   +1 more source

Normalized solutions for critical Schrödinger equations involving (2,q)-Laplacian [PDF]

Opuscula Mathematica
In this paper, we consider the following critical Schrödinger equation involving \((2,q)\)-Laplacian: \[\begin{cases} -\Delta u-\Delta_{q} u=\lambda u+\mu |u|^{\gamma-2}u+|u|^{2^*-2}u \quad\text{in }\mathbb{R}^N, \\ \int_{\mathbb{R}^N} |u|^{2}dx=a^2,\end{
Lulu Wei, Yueqiang Song
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source