Results 41 to 50 of about 163,087 (265)

Concentration camp photograph #7

open access: yes, 1945
Black-and-white photograph taken at a concentration camp about 2 kilometers northwest of Landsberg, Germany, in 1945. Described in a memo to the commanding general VI Corps, 28 April 1945 as: "This young man was wounded three years ago. Part of bone
United States. Army;
core  

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

open access: yesAdvanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Concentration camp photograph #6

open access: yes, 1945
Black-and-white photograph taken at a concentration camp about 2 kilometers northwest of Landsberg, Germany, in 1945. Described in a memo to the commanding general VI Corps, 28 April 1945 as: "Seven bodies awaiting burial.
United States. Army;
core  

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Concentration camp photograph #8

open access: yes, 1945
Black-and-white photograph taken at a concentration camp about 5 kilometers north of Landsberg, Germany, in 1945. Described in a memo to the commanding general VI Corps, 28 April 1945 as: "There were 47 bodies in this pile.
United States. Army;
core  

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

Concentration camp photograph #9

open access: yes, 1945
Black-and-white photograph taken at a concentration camp about 5 kilometers north of Landsberg, Germany, in 1945. Described in a memo to the commanding general VI Corps, 28 April 1945 as: "There were 47 bodies in this pile.
United States. Army;
core  

Quantitative Analysis of Cell Motility and Chemotaxis in Dictyostelium discoideum by Using an Image Processing System and a Novel Chemotaxis Chamber Providing Stationary Chemical Gradients

open access: yes, 1989
An image processing system was programmed to automatically track and digitize the movement of amebae under phase-contrast microscopy. The amebae moved in a novel chemotaxis chamber designed to provide stable linear attractant gradients in a thin agarose ...
G Gerisch   +5 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

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