Results 51 to 60 of about 163,087 (265)

Concentration camp photograph #5

open access: yes, 1945
Black-and-white photograph taken at a concentration camp about 2 kilometers northwest of Landsberg, Germany, in 1945. Described in a memo to the commanding general VI Corps, 28 April 1945 as: "Burial pit parially filled.
United States. Army;
core  

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

open access: yesAdvanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska   +14 more
wiley   +1 more source

Concentration camp photograph #13

open access: yes, 1945
Black-and-white photograph taken at a concentration camp about 5 kilometers north of Landsberg, Germany, in 1945. Described in a memo to the commanding general VI Corps, 28 April 1945 as: "Clothing partially burned.
United States. Army;
core  

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

open access: yesAdvanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao   +12 more
wiley   +1 more source

Concentration camp photograph #4

open access: yes, 1945
Black-and-white photograph taken at a concentration camp about 2 kilometers northwest of Landsberg, Germany, in 1945. Described in a memo to the commanding general VI Corps, 28 April 1945 as: "Burial grounds.
United States. Army;
core  

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan   +12 more
wiley   +1 more source

Concentration camp photograph #15

open access: yes, 1945
Black-and-white photograph taken at a concentration camp about 5 kilometers north of Landsberg, Germany, in 1945. Described in a memo to the commanding general VI Corps, 28 April 1945 as: "Incision for castration had not started to heal.
United States. Army;
core  

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

Concentration camp photograph #2

open access: yes, 1945
Black-and-white photograph taken at a concentration camp about 2 kilometers northwest of Landsberg, Germany, in 1945. Described in a memo to the commanding general VI Corps, 28 April 1945 as: "Body in the street, number tattooed on chest.
United States. Army;
core  

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

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