Results 41 to 50 of about 4,640 (267)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Concentration-Compactness Principle for embedding into multiple exponential spaces [PDF]
Mathematical Inequalities & Applications, 2012 Let Ω⊂Rn , n 2 , be a bounded domain and let α < n−1 . We prove the ConcentrationCompactness Principle for the embedding of the Orlicz-Sobolev space W 1 0 L n logn−1 L logα logL(Ω) into the Orlicz space corresponding to a Young function that behaves like exp(exp(t n n−1−α )) for large t .
openaire +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Solutions for the quasi-linear elliptic problems involving the critical Sobolev exponent
Journal of Inequalities and Applications, 2017 In this article, we study the existence and multiplicity of positive solutions for the quasi-linear elliptic problems involving critical Sobolev exponent and a Hardy term.
Yanbin Sang, Siman Guo
doaj +1 more source
Existence of ground state for fractional Kirchhoff equation with L 2 $L^{2}$ critical exponents
Boundary Value Problems, 2020 In this paper, we consider a class of fractional Kirchhoff equations with L 2 $L^{2}$ critical exponents. By using the scaling technique and concentration-compactness principle we obtain the existence and nonexistence of ground state for fractional ...
Yaling Han, Yimin Zhang
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A study and an application of the concentration compactness type principle
, 2019 In this article we develop a concentration compactness type principle in a variable exponent setup. As an application of this principle we discuss a problem involving fractional `{\it $(p(x),p^+)$-Laplacian}' and power nonlinearities with exponents $(p^+)^*$, $p_s^*(x)$ with the assumption that the critical set $\{x\inΩ:p_s^*(x)=(p^+)^*\}$ is nonempty.
Panda, Akasmika, Choudhuri, Debajyoti
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Critical singular problems via concentration-compactness lemma [PDF]
, 2007 In this work we consider existence and multiplicity results of nontrivial solutions for a class of quasilinear degenerate elliptic equations in RN of the form(P)−div[|x|−ap|∇u|p−2∇u]+λ|x|−(a+1)p|u|p−2u=|x|−bq|u|q−2u+f, where x∈RN ...
Carrião, Paulo Cesar +2 more
core +1 more source