Results 81 to 90 of about 3,167,057 (258)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Determinants of medical borrowing and associated inequalities in the Kingdom of Saudi Arabia: evidence from the Global Findex survey

Health Economics Review
Background While out-of-pocket health expenses continue to rise, households’ coping strategies remain largely unexplored. When individuals and families rely on unsustainable mechanisms such as borrowing, they may face heightened financial vulnerability ...
Mohammed Khaled Al-Hanawi
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

The Lorenz curve in economics and econometrics [PDF]

This paper surveys selected applications of the Lorenz curve and related stochastic orders in economics and econometrics, with a bias towards problems in statistical distribution theory. These include characterizations of income distributions in terms of
Christian Kleiber
core  

Urban Concentration and Spatial Allocation of Rents from natural resources. A Zipf's Curve Approach

REGION, 2017
This paper aims at demonstrating how countries' dependency on natural resources plays a crucial role in urban concentration. The Zipf's Curve Elasticity is estimated for a group of countries and related to a set of indicators of unilateral transferences.
Tomaz Ponce Dentinho
doaj   +1 more source

Sound concentration caused by curved surfaces [PDF]

Proceedings of Meetings on Acoustics, 2013
In room acoustics, the focusing effect of reflections from concave surfaces is a well-known problem. The occurrence of concave surfaces has tended to increase in modern architecture, due to new techniques in design, materials, and manufacturing. Focusing can cause high sound pressure levels, sound coloration, or an echo.
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Concentration curve of income factors.

Note: In the depicted figure, the x-axis indicates the population distribution across quantiles, while the y-axis shows the income distribution. The Lorenz curve for income is denoted by L(y, p), whereas L(w, p) and L(π, p) represent the concentration ...
Jing Zheng (65946), Xunhua Tu (16814341), Jie Yan (119530)   +2 more
core   +1 more source

The Forms of Antagonism Curves as Affected by Concentration [PDF]

Botanical Gazette, 1914
A study of the literature shows that the effect of concentration on the form of the antagonism curve is not fully appreciated. The alterations in the form of the curve are very marked when solutions are diluted to one-half strength. The writer has found this to be the case with antagonism curves of different types obtained by using a great variety of ...
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source