Results 91 to 100 of about 7,830,732 (295)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Exploring the spatial variation of intra-urban housing prices based on inverse S-function fitting of 35 cities

open access: yesFrontiers in Built Environment
Housing prices serve as a crucial indicator of macroeconomic stability and urban spatial vitality. However, existing studies on intra-urban housing prices predominantly focus on single-city empirical analyses or localized examinations of individual ...
Xiaojin Liang   +13 more
doaj   +1 more source

Measuring income related inequality in health and health care: the partial concentration index with direct and indirect standardisation. [PDF]

open access: yes
The partial concentration index measures income related inequality in health (or health care) after removing the effects of standardising variables which affect health (or health care), are correlated with income but not amenable to policy.
Hugh Gravelle
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Socioeconomic inequity in extreme outcomes within very pre-term and/or very low birthweight infants: evidence from multi-national cohorts

open access: yesFrontiers in Public Health
BackgroundPre-term birth (< 37 weeks' gestation) is a major cause of neonatal mortality, with very pre-term (< 32 weeks' gestation) and extremely pre-term (< 28 weeks' gestation) infants facing the highest risks.
Hanifa Pilvar   +16 more
doaj   +1 more source

Socioeconomic inequality in Hepatitis B vaccination of rural adults in China

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Hepatitis B (HB) vaccination is the most effective way to prevent HB virus infection. While measures taken to control the prevalence of HB have achieved significant results, HB prevalence in rural China among adults remains problematic.
Dawei Zhu   +7 more
doaj   +1 more source

The Interpretation of the Laakso-Taagepera Effective Number of Parties [PDF]

open access: yes
In this paper, we present a general statistical framework within which we can draw a new interpretation of the Laakso-Taagepera effective number of parties fragmentation index.
Jean-François Caulier
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Socioeconomic inequalities in unmet dental care needs in Spain

open access: yesFrontiers in Oral Health
ObjectiveSocioeconomic inequalities in access to dental care remain a critical public health challenge in Spain, where adult coverage is limited and largely financed through out-of-pocket payments.
Sergio Zuniga-Jara   +3 more
doaj   +1 more source

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