Results 81 to 90 of about 7,830,732 (295)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Investigation of Status of Socioeconomic Inequalities in Satisfaction with Life in Women Aged 15-54 in Iran

open access: yesمجله اپیدمیولوژی ایران, 2018
Background and Objectives: Life satisfaction is one of the important dimensions of health, which is influenced by health determinants. The aim of this study was to investigate the status of socioeconomic inequalities in satisfaction with life in women ...
E Goodarzi   +7 more
doaj  

Inequalities changes in health services utilization among middle-aged and older adult disabled people in China: based on CHARLS 2011–2018

open access: yesFrontiers in Public Health
BackgroundMultiple intersections, including socioeconomic inequalities, influence health equity for disabled people and sub-populations. However, this association has not been sufficiently analyzed among Chinese-impaired persons.
Shengxuan Jin   +9 more
doaj   +1 more source

Price and Cost Impacts of Concentration in Food Manufacturing Revisited [PDF]

open access: yes
This study estimates the elasticities of wholesale food prices, cost efficiency, and market power with respect to industrial concentration in 35 food processing industries, modifying the model of Lopez, Azzam, and Lirón-España (2002).
Liron-Espana, Carmen   +1 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Exploring the Individual, Socioeconomic and Contextual Determinants Associated with Daily Tobacco Consumption in Portugal

open access: yesNotas Económicas
The National Program for Tobacco Prevention and Control reflects awareness of tobacco as a major public health problem in Portugal. To infer which population groups should be targeted, we estimate sex-specific logistic regressions to analyze the ...
Laura Almeida   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Measuring socioeconomic inequalities in postnatal health checks for newborns in Ethiopia: a decomposition analysis

open access: yesFrontiers in Public Health
BackgroundAddressing health inequity is a top priority for achieving sustainable development goals. The existing evidences in Ethiopia have shown that there are substantial inequalities in the use of health services among various socioeconomic strata ...
Asebe Hagos   +16 more
doaj   +1 more source

Calculating the concentration index when income is grouped

open access: yesJournal of Health Economics, 2010
The problem introduced by grouping income data when measuring socioeconomic inequalities in health (and health care) has been highlighted in a recent study in this journal. We re-examine this issue and show there is a tendency to underestimate the concentration index at an increasing rate when lowering the number of income categories.
Clarke, P, Van Ourti, Tom
openaire   +3 more sources

Benchmark Concentration: Capitalization Weights Versus Equal Weights in the FTSE 100 Index [PDF]

open access: yes, 2009
Identifying a suitable benchmark is essential when testing asset pricing models, measuring the performance of active investors, or providing market proxy portfolios for passive investors. Concern that increased domination of capitalization weighted stock
Tabner, Isaac
core  

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