Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Development of competition indicators in the Norwegian general practice: Constructing a postal code-specific Herfindahl-Hirschman index applying STATA software [PDF]
The purpose of this text is to describe a procedure that can be used to construct a Herfindahl-Hirschman index of market concentration based on the following two pieces of information: a) An output measure of individual producers located in areas ...
Chen, Xing, Godager, Geir
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Concentration curve and Concentration Index (CI), years 2009 and 2013.
, 2019 Concentration curve and Concentration Index (CI), years 2009 and 2013.
Iris Delgado (632679) +8 more
core +1 more source
Sales concentration index in the Iranian car market [PDF]
, 2015 Concentration is among the key indicators of market structure. The number of manufacturers and distribution of market between firms with different sizes can be examined using concentration index.
Kazemzadeh Emad, Sheikh Zeinoddin Azar
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Spatial variability of concentration and aggressiveness of precipitation in North-East of Algeria
Journal of Water and Land Development, 2018 In this study, the spatial variation of daily and monthly concentration precipitation index and its aggressiveness were used in 23 rainfall stations in the extreme north-east of Algeria over the period 1970–2010.
Bessaklia Hanene +3 more
doaj +1 more source
Trends and determinants of anaemia in women of Nepal: a multilevel analysis
Maternal and Child Nutrition, 2020 In Nepal, the prevalence of anaemia decreased by 1% from 2006 to 2011 but increased by 6% from 2011 to 2016. In this study, we examined the changes in prevalence by possible factors from 2006 to 2016 along with the factors associated with anaemia among ...
Anjana Rai +2 more
doaj +1 more source
Spatial Point Pattern Analysis and Industry Concentration [PDF]
Traditional measures of spatial industry concentration are restricted to given areal units. They do not make allowance for the fact that concentration may be differently pronounced at various geographical levels. Methods of spatial point pattern analysis
Hans-Friedrich Eckey +2 more
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